| Gene Symbol | OR51E2 |
|---|---|
| Entrez Gene | 81285 |
| Alt Symbol | OR51E3P, OR52A2, PSGR |
| Species | Human |
| Gene Type | protein-coding |
| Description | olfactory receptor, family 51, subfamily E, member 2 |
| Other Description | HPRAJ|olfactory receptor 51E2|olfactory receptor OR11-16|olfactory receptor, family 51, subfamily E, member 3 pseudogene|olfactory receptor, family 52, subfamily A, member 2|prostate specific G-protein coupled receptor|prostate-specific G-protein coupled receptor |
| Swissprots | Q9H255 B2RA63 Q6IF94 |
| Accessions | AAG40776 CAJ56785 DAA04766 EAW68829 EAW68831 Q9H255 AF369708 AAK38728 AK314051 BAG36760 AY033942 AAK57550 BC020768 AAH20768 DQ892702 ABM83628 DQ895946 ABM86872 NM_030774 NP_110401 |
| Function | Probable G protein-coupled receptor that is activated by the short chain fatty acids (SCFA) acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure (PubMed:23401498). May also be activated by steroid hormones and regulate cell proliferation (PubMed:19389702). May also function as an olfactory receptor being activated by beta-ionone (PubMed:19389702). {ECO:0000269|PubMed:19389702, ECO:0000269|PubMed:23401498}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:23401498}; Multi-pass membrane protein {ECO:0000269|PubMed:23401498}. |
| Tissue Specificity | Mainly expressed in the prostate. Also expressed in spleen, liver, olfactory epithelium and medulla oblongata. {ECO:0000269|PubMed:11707321, ECO:0000269|PubMed:16491480}. |
| Top Pathways | Olfactory transduction |