HPN
| Gene Symbol | HPN |
|---|---|
| Entrez Gene | 3249 |
| Alt Symbol | TMPRSS1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | hepsin |
| Other Description | serine protease hepsin|transmembrane protease serine 1 |
| Swissprots | B2RDS4 P05981 |
| Accessions | CAC60387 CCQ43929 P05981 AK091988 AK095160 AK293622 BAH11550 AK315655 BAG38021 BC025716 AAH25716 DQ892119 ABM83045 DQ895314 ABM86240 EU644753 ACD02430 M18930 AAA36013 X07002 CAA30058 X07732 CAA30558 XM_005258838 XP_005258895 XM_006723181 XP_006723244 XM_011526891 XP_011525193 NM_002151 NP_002142 NM_182983 NP_892028 |
| Function | Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2. {ECO:0000269|PubMed:15839837, ECO:0000269|PubMed:21875933, ECO:0000269|PubMed:24227843}. |
| Subcellular Location | Membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Present in most tissues, with the highest level in liver. |
| Top Pathways | Viral carcinogenesis |
HPN-Over-expression-Lysate - LY14674a from Abgent, a WuXi AppTec company
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HPN overexpression lysate - LY400781 from Acris Antibodies
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HPN overexpression lysate - LY405297 from Acris Antibodies
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HPN 293 Cell Lysate - 400750 from ABBIOTEC
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HPN 293 Cell Lysate - 403570 from ABBIOTEC
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Hepsin Overexpression Lysate (Native) - NBL1-11695 from Novus Biologicals
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Hepsin Overexpression Lysate (Native) - NBL1-11694 from Novus Biologicals
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HPN Over-expression Lysate Product - GWB-4602DE from Genway Biotech
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HPN Over-expression Lysate Product - GWB-30D096 from Genway Biotech
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Panoply™ Human HPN Knockdown Stable Cell Line - CSC-DC007230 from Creative biogene
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