HPN

Gene Symbol HPN
Entrez Gene 3249
Alt Symbol TMPRSS1
Species Human
Gene Type protein-coding
Description hepsin
Other Description serine protease hepsin|transmembrane protease serine 1
Swissprots B2RDS4 P05981
Accessions CAC60387 CCQ43929 P05981 AK091988 AK095160 AK293622 BAH11550 AK315655 BAG38021 BC025716 AAH25716 DQ892119 ABM83045 DQ895314 ABM86240 EU644753 ACD02430 M18930 AAA36013 X07002 CAA30058 X07732 CAA30558 XM_005258838 XP_005258895 XM_006723181 XP_006723244 XM_011526891 XP_011525193 NM_002151 NP_002142 NM_182983 NP_892028
Function Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2. {ECO:0000269|PubMed:15839837, ECO:0000269|PubMed:21875933, ECO:0000269|PubMed:24227843}.
Subcellular Location Membrane; Single-pass type II membrane protein.
Tissue Specificity Present in most tissues, with the highest level in liver.
Top Pathways Viral carcinogenesis

Hepsin CRISPR/Cas9 KO Plasmid (h) - sc-405081 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hepsin HDR Plasmid (h) - sc-405081-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hepsin Double Nickase Plasmid (h) - sc-405081-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hepsin Double Nickase Plasmid (h2) - sc-405081-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hepsin CRISPR Activation Plasmid (h) - sc-405081-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hepsin CRISPR Activation Plasmid (h2) - sc-405081-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hepsin Lentiviral Activation Particles (h) - sc-405081-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hepsin Lentiviral Activation Particles (h2) - sc-405081-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Hepsin siRNA (h) - sc-60782 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Hepsin shRNA Plasmid (h) - sc-60782-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Hepsin shRNA (h) Lentiviral Particles - sc-60782-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Hepsin RNAi - H00003249-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Hepsin RNAi - H00003249-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU061661 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10277 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10277 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02313 from Sigma-Aldrich

Category miRNA

HPN siRNA (Human) - CRH2228 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HPN - MBS8219737 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HPN (NM_002151.2) - SHH314617 from Creative biogene

Category siRNA
Species Reactivities Human

Human HPN siRNA - orb262730 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HPN shRNA Plasmid (Human) - CHH2228 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HPN miRNA 3'UTR clone - MiUTR3H-01032 from Creative biogene

Species Reactivities Human

HPN miRNA 3'UTR clone - MiUTR3H-01033 from Creative biogene

Species Reactivities Human
Search more