XPO7

Gene Symbol XPO7
Entrez Gene 23039
Alt Symbol EXP7, RANBP16
Species Human
Gene Type protein-coding
Description exportin 7
Other Description RAN binding protein 16|exportin-7
Swissprots Q8NEK7 Q9UIA9 Q6PJK9 O94846
Accessions EAW63733 EAW63734 EAW63735 EAW63736 Q9UIA9 AB018288 BAA34465 AF064729 AAF21771 AK291472 BAF84161 AK299848 BAG61710 AK311616 AL597247 BC014219 AAH14219 BC030785 AAH30785 CN479571 DB460798 DC332379 NM_001100161 NM_001100162 NM_015024 NP_055839
Function Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. {ECO:0000269|PubMed:11024021, ECO:0000269|PubMed:15282546}.
Subcellular Location Cytoplasm. Nucleus {ECO:0000305}. Nucleus, nuclear pore complex {ECO:0000305}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000305}.
Tissue Specificity Strong expression in testis, thyroid and bone marrow, low expression in lung, liver and small intestine, no expression in thymus, and remaining tissues studied have moderate expression. Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. {ECO:0000269|PubMed:11071879, ECO:0000269|PubMed:22509282}.

Exportin 7 (H-82) - sc-98639 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Exportin 7 (A-11) - sc-390025 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Exportin 7 (A-11): sc-390025. Western blot analysis of Exportin 7 expression in non-transfected: sc-117752 (A) and mouse Exportin 7 transfected: sc-120146 (B) 293T whole cell lysates.

Anti-RanBP16 antibody - ab6041 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-XPO7 / RANBP16 Antibody (aa1075-1087) IHC-plus™ - LS-B2854 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-XPO7 / RANBP16 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2854 concentration 5 ug/ml.

Anti-XPO7 / RANBP16 Antibody (aa1004-1053) - LS-C186774 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human 721_B. XPO7 antibody dilution 1.0 ug/ml.

Anti-XPO7 / RANBP16 Antibody (aa902-1087) - LS-C185469 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded lung SCC using RanBP16 antibody at 1:100 dilution.

RanBP16 Antibody - NBP1-32350 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RanBP16 Antibody [NBP1-32350] - Sample(30 ug of whole cell lysate)A:H1299 B:HeLa S3 7. 5% SDS PAGE, antibody diluted at 1:500.

RanBP16 Antibody - NB100-1378 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: RanBP16 Antibody [NB100-1378] - Western blot analysis of RANBP16 in Hela lysate using NB100-1378 at 0.5 ug/ ml.

Anti-RANBP16/Ecportin 7 antibody produced in goat - SAB2500864 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RANBP16 / Exportin 7: <B>Cat. No. SAB2500864</B>: staining (0.5 μg/mL) of HeLa lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-XPO7 antibody produced in rabbit - HPA043727 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-XPO7: <B>Cat. No. HPA043727</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in Leydig cells and a subset of cells in seminiferus ducts.

Anti-XPO7 (C-terminal) antibody produced in rabbit - SAB2700250 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-XPO7 (C-terminal): <B>Cat. No. SAB2700250</B>: Immunohistochemical analysis of paraffin-embedded Lung SCC, using RanBP16 antibody at 1:100 dilution.

Anti-XPO7 antibody produced in rabbit - HPA048153 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-XPO7: <B>Cat. No. HPA048153</B>: Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in astrocytes.

RANBP17 Antibody - C-terminal region (ARP65486_P050) - ARP65486_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RANBP16--Exportin-7-Antibody - AF1908a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1908a staining (0.5 µg/ml) of Hela lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

RanBP16 antibody - orb73596 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:H1299, B:Hela S3 whole cell lysate using RanBP16 antibody

XPO7 antibody - orb25124 from Biorbyt

Prices $357.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human testis carcinoma tissue using anti-XPO7 antibody

Goat Anti-RANBP16 / Exportin 7 Antibody (OAEB01565) - OAEB01565 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

RanBP16 antibody - 70R-12651 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

XPO7 antibody (OAGA00165) - OAGA00165 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

XPO7 Polyclonal Antibody - A4524 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

XPO7 antibody - orb88511 from Biorbyt

Prices $536.00
Sizes 50 μg
Host Goat
Clonality Polyclonal
Immunohistochemical staining of paraffin embedded human testis tissue using XPO7 antibody (primary antibody at 1:200)

XPO7 Antibody (OALA02928) - OALA02928 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

XPO7 antibody - 70R-21345 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

XPO7 Antibody - abx007648 from Abbexa

Host Rabbit
Clonality Polyclonal

XPO7 Antibody - abx007647 from Abbexa

Host Rabbit
Clonality Polyclonal
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