CD14

Gene Symbol	CD14
Entrez Gene	929
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	CD14 molecule
Other Description	monocyte differentiation antigen CD14|myeloid cell-specific leucine-rich glycoprotein
Swissprots	Q9UNS3 Q53XT5 Q96L99 P08571 Q96FR6
Accessions	AAA20640 ADX31876 CAA29999 EAW62037 P08571 AB446505 BAG55282 AF097942 AAC83816 AK313277 BAG36085 AM392692 CAL37570 AM392824 CAL37702 AM393386 CAL38264 AM393697 CAL38573 AY044269 AAL02401 BC010507 AAH10507 BP300412 BT007331 AAP35995 CF593452 DA269805 DA426297 DA681405 M86511 AAA51930 W74441 X13334 CAA31711 NM_000591 NP_000582 NM_001040021 NP_001035110 NM_001174104 NP_001167575 NM_001174105 NP_001167576
Function	In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. {ECO:0000269|PubMed:23264655}.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity	Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
Top Pathways	Legionellosis, Tuberculosis, Salmonella infection, Amoebiasis, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CD14-Over-expression-Lysate - LY10841a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

CD14 293T Cell Transient Overexpression Lysate(Denatured) - H00000929-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CD14 293T Cell Transient Overexpression Lysate(Denatured) - H00000929-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CD14 overexpression lysate - LY421877 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CD14 overexpression lysate - LY424624 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CD14 293 Cell Lysate - 409580 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CD14 293 Cell Lysate - 410184 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CD14 Overexpression Lysate (Denatured) - H00000929-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

CD14 Overexpression Lysate (Denatured) - H00000929-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

CD14 Overexpression Lysate (Native) - NBL1-08905 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CD14 Overexpression Lysate (Native) - NBL1-08906 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CD14 (h): 293 Lysate - sc-112351 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CD14 (h3): 293 Lysate - sc-128274 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CD14 Over-expression Lysate Product - GWB-E91B08 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

CD14 Over-expression Lysate Product - GWB-38F7EC from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human CD14 Knockdown Stable Cell Line - CSC-DC002698 from Creative biogene Category Cell Line Species Human

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