CD14

Gene Symbol	CD14
Entrez Gene	929
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	CD14 molecule
Other Description	monocyte differentiation antigen CD14|myeloid cell-specific leucine-rich glycoprotein
Swissprots	Q9UNS3 Q53XT5 Q96L99 P08571 Q96FR6
Accessions	AAA20640 ADX31876 CAA29999 EAW62037 P08571 AB446505 BAG55282 AF097942 AAC83816 AK313277 BAG36085 AM392692 CAL37570 AM392824 CAL37702 AM393386 CAL38264 AM393697 CAL38573 AY044269 AAL02401 BC010507 AAH10507 BP300412 BT007331 AAP35995 CF593452 DA269805 DA426297 DA681405 M86511 AAA51930 W74441 X13334 CAA31711 NM_000591 NP_000582 NM_001040021 NP_001035110 NM_001174104 NP_001167575 NM_001174105 NP_001167576
Function	In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. {ECO:0000269|PubMed:23264655}.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity	Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
Top Pathways	Legionellosis, Tuberculosis, Salmonella infection, Amoebiasis, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CD14-cDNA-Clone - DC02941 from Abgent, a WuXi AppTec company Prices $506.25 Sizes 10 µg Species Human Accession BC010507

Mouse CD14 (NP_033971) VersaClone cDNA - RDC1212 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

Human CD14 (NP_000582) VersaClone cDNA - RDC1172 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

CD14 - MBS1276223 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC010507

Human CD14 transcript variant 1 Gene ORF cDNA clone in cloning vector - HG10073-M from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10073-CY from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid - HG10073-UT from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10073-CH from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10073-NY from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10073-NF from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10073-M-F from Sino Biological Species Human

Human CD14 transcript variant 1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10073-M-N from Sino Biological Species Human Accession NM_000591.2

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10073-CF from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10073-ACG from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10073-NM from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10073-CM from Sino Biological Species Human

Human CD14 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10073-NH from Sino Biological Species Human

Human CD14 ORF Clone(NM_001174104.1) - CDCR356799 from Creative biogene Species Human

Human CD14 ORF Clone(NM_001174105.1) - CDCR356951 from Creative biogene Species Human

Human CD14 ORF Clone (BC010507) - CDCS405776 from Creative biogene Species Human Accession P08571

Human CD14 cDNA Clone(NM_001174105.1) - CDFH003037 from Creative biogene Species Human

Human CD14 cDNA Clone(NM_001174104.1) - CDFH003038 from Creative biogene Species Human

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