CD14

Gene Symbol	CD14
Entrez Gene	929
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	CD14 molecule
Other Description	monocyte differentiation antigen CD14|myeloid cell-specific leucine-rich glycoprotein
Swissprots	Q9UNS3 Q53XT5 Q96L99 P08571 Q96FR6
Accessions	AAA20640 ADX31876 CAA29999 EAW62037 P08571 AB446505 BAG55282 AF097942 AAC83816 AK313277 BAG36085 AM392692 CAL37570 AM392824 CAL37702 AM393386 CAL38264 AM393697 CAL38573 AY044269 AAL02401 BC010507 AAH10507 BP300412 BT007331 AAP35995 CF593452 DA269805 DA426297 DA681405 M86511 AAA51930 W74441 X13334 CAA31711 NM_000591 NP_000582 NM_001040021 NP_001035110 NM_001174104 NP_001167575 NM_001174105 NP_001167576
Function	In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. {ECO:0000269|PubMed:23264655}.
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Specificity	Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
Top Pathways	Legionellosis, Tuberculosis, Salmonella infection, Amoebiasis, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CD14 full length protein - ab167706 from Abcam Category Protein Prices $352.00 Sizes 100 µg Source HEK 293 cells Species Human

Active human CD14 full length protein - ab168687 from Abcam Category Protein Prices $352.00 Sizes 100 µg Source HEK 293 cells Species Human

CD14 peptide (71-84) - ab45882 from Abcam Category Peptide Prices $290.00 Sizes 100 µg Species Human

Human CD14 full length protein - ab132926 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human CD14 full length protein - ab181959 from Abcam Category Protein Prices $301.00 Sizes 50 µg Source E. coli Species Human

Human CD14 full length protein - ab134898 from Abcam Category Protein Prices $188.00 Sizes 100 µg Source E. coli Species Human

Human CD14 full length protein - ab151366 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human CD14 protein fragment - ab82279 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

CD14-Antibody-C-term-Blocking-Peptide - BP6294b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CD14-Antibody-N-term-Blocking-Peptide - BP6294a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human CD14 - 383-CD-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Thr20-Cys352

Recombinant Human CD14, CF - 383-CD-050/CF from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Thr20-Cys352

Recombinant Mouse CD14 Fc Chimera, CF - 982-CD-100 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

CD14 Protein (OPPA01422) - OPPA01422 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg

Human CD14 protein - orb246916 from Biorbyt Category Protein Prices $502.00, $774.00, $1,054.00 Sizes 20 μg, 50 μg, 100 μg Species Human

Human CD14 protein - orb244082 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

CD14 protein (His tag) - 80R-3830 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

Human CD14 Protein - abx065911 from Abbexa Category Protein Source E.coli Species Human

CD14 Peptide - AC21-0859-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CD14 (His-tag) - AR51517PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

CD14 (His-tag) - AR51517PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

CD14 - H00000929-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD14 - H00000929-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CD14 - P4167 from Acris Antibodies Category Protein Prices $790.00 Sizes 10 µg Species Human

CD14 - P6141 from Acris Antibodies Category Protein Prices $580.00 Sizes 50 µg Species Human

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