Gene Symbol | VAV2 |
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Entrez Gene | 7410 |
Alt Symbol | VAV-2 |
Species | Human |
Gene Type | protein-coding |
Description | vav 2 guanine nucleotide exchange factor |
Other Description | guanine nucleotide exchange factor VAV2|vav 2 oncogene |
Swissprots | Q5SYV5 Q6N012 A2RUM4 P52735 Q6Q317 A8MQ12 B6ZDF5 Q5SYV3 Q5SYV4 Q6PIJ9 |
Accessions | EAW88107 EAW88108 EAW88109 P52735 AJ420448 AK091622 AK123314 AK124271 BAC85822 AK130575 AM393013 CAL37891 AM393506 CAL38383 AY563001 AAS75591 BC033187 AAH33187 BC043615 BC128448 BC132965 AAI32966 BC132967 AAI32968 BQ050947 BQ071939 BX640754 CAE45861 S76992 AAB34377 XM_005272213 XP_005272270 XM_006717277 XP_006717340 XM_011518983 XP_011517285 XM_011518984 XP_011517286 NM_001134398 NP_001127870 NM_003371 NP_003362 |
Function | Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). {ECO:0000250}. |
Tissue Specificity | Widely expressed. |
Top Pathways | Proteoglycans in cancer, cAMP signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Focal adhesion |
VAV2 Antibody Blocking Peptide - LS-E25312 from LifeSpan Bioscience
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VAV2-Antibody-Center-Blocking-Peptide - BP9734c from Abgent, a WuXi AppTec company
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VAV2 blocking peptide - GTX24549-PEP from GeneTex
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VAV2 peptide - orb218079 from Biorbyt
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VAV2 Blocking Peptide - abx063410 from Abbexa
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VAV2 Peptide - AC21-0140-P from Abcore
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VAV2 Peptide - 45-168P from ProSci
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VAV2 fusion protein - Ag16458 from Proteintech Group
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VAV2 fusion protein - ag17988 from Proteintech Group
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Recombinant Human VAV2, GST-tagged - VAV2-3653H from Creative Biomart
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VAV2 Blocking Peptide - CBP2216 from Cohesion Biosciences
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VAV2 (D138) Peptide - BS2443P from Bioworld Technology
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Recombinant Human Guanine nucleotide exchange factor VAV2(VAV2) ,partial - CSB-YP025804HU CSB-EP025804HU CSB-BP025804HU CSB-MP025804HU from Cusabio
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Vav2 (a.a. 137-147) - VX2575 from ECM Biosciences
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Vav2 (a.a. 165-174) - VX2485 from ECM Biosciences
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Vav2 (a.a. 309-322) - VX2525 from ECM Biosciences
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VAV2 (transcript variant 2) - TP316175 from Acris Antibodies
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VAV2, Peptide - MBS425097 from MyBioSource
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VAV2 (pY142) Blocking Peptide - abx162073 from Abbexa
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VAV2 Recombinant Protein Antigen - NBP1-86520PEP from Novus Biologicals
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VAV2 Peptide, Human - M34GP17244H from Creative Peptides
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VAV2 (pY142) Blocking Peptide - CBP4862 from Cohesion Biosciences
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Guanine nucleotide exchange factor VAV2 (VAV2), partial, Recombinant Protein - MBS961364 from MyBioSource
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VAV2 (Phospho-Y142) peptide - orb316006 from Biorbyt
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