CNGB3

Gene Symbol CNGB3
Entrez Gene 54714
Alt Symbol ACHM1
Species Human
Gene Type protein-coding
Description cyclic nucleotide gated channel beta 3
Other Description CNG channel beta-3|cone photoreceptor cGMP-gated cation channel beta-subunit|cyclic nucleotide-gated cation channel beta-3|cyclic nucleotide-gated cation channel modulatory subunit
Swissprots Q9NQW8 Q9NRE9 C9JA51
Accessions EAW91644 EAW91645 EAW91646 Q9NQW8 AF228520 AAF80179 AF272900 AAF86274 AL713036 BC150601 AAI50602 BX118844 DQ426865 ABD90531 XM_011517138 XP_011515440 NM_019098 NP_061971
Function Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones. {ECO:0000250, ECO:0000269|PubMed:10888875}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed specifically in the retina. {ECO:0000269|PubMed:10958649}.
Top Pathways cAMP signaling pathway

CNG-β3 (C-16) - sc-34990 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CNG-β3 (C-16): sc-34990. Western blot analysis of CNG-β3 expression in ARPE-19 whole cell lysate.

CNG-β3 (H-233) - sc-98791 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CNG-β3 (K-20) - sc-34992 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CNG-β3 (K-20): sc-34992. Western blot analysis of CNG-β3 expression in Y79 (A), T98G (B), ARPE-19 (C), H4 (D) and NTERA-2 cl.D1 (E) whole cell lysates.

CNG-β3 (N-20) - sc-34993 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CNGB3 antibody - ab113056 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CNGB3 antibody (ab113056) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg

Anti-CNGB3 / CNG Channel Beta-3 Antibody (aa33-63, AP) - LS-C234023 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGB3 / CNG Channel Beta-3 Antibody (aa33-63, APC) - LS-C234026 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGB3 / CNG Channel Beta-3 Antibody (aa33-63, Biotin) - LS-C234027 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGB3 / CNG Channel Beta-3 Antibody (aa33-63, FITC) - LS-C234028 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGB3 / CNG Channel Beta-3 Antibody (aa33-63, Azide-free, HRP) - LS-C249711 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGB3 / CNG Channel Beta-3 Antibody (aa33-63, PE) - LS-C234032 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGB3 / CNG Channel Beta-3 Antibody (aa33-63) - LS-C320477 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGB3 / CNG Channel Beta-3 Antibody (N-Terminus) - LS-C345654 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of CNGB3 Antibody with human MCF7 Whole Cell lysate.

Anti-CNGB3 / CNG Channel Beta-3 Antibody (aa33-63) - LS-C168877 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CNGB3 Antibody western blot of MDA-MB435 cell line lysates (35 ug/lane). The CNGB3 antibody detected the CNGB3 protein (arrow).

CNGB3 Antibody - NBP1-46277 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CNGB3 Polyclonal Antibody - bs-12094R from Bioss

Clonality Polyclonal
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