Gene Symbol | GABRG2 |
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Entrez Gene | 2566 |
Alt Symbol | CAE2, ECA2, GEFSP3 |
Species | Human |
Gene Type | protein-coding |
Description | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
Other Description | GABA(A) receptor subunit gamma-2|GABA(A) receptor, gamma 2|gamma-aminobutyric acid receptor subunit gamma-2 |
Swissprots | Q6GRL6 Q9UN15 P18507 Q9UDB3 F5HB82 Q6PCC3 |
Accessions | AAD50273 EAW61532 EAW61533 EAW61534 EAW61535 P18507 AK123394 AK299640 BAG61563 AK315200 BC036030 BC052926 BC059389 AAH59389 BC069348 AAH69348 BC074795 AAH74795 CD013896 CD013897 DA226729 X15376 CAA33437 NM_000816 NP_000807 NM_198903 NP_944493 NM_198904 NP_944494 |
Function | Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel. {ECO:0000269|PubMed:2538761}. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane {ECO:0000269|PubMed:2538761}; Multi-pass membrane protein {ECO:0000269|PubMed:2538761}. Cell membrane {ECO:0000269|PubMed:2538761}; Multi-pass membrane protein {ECO:0000269|PubMed:2538761}. |
Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |
Human GABA A Receptor gamma 2 peptide - ab98295 from Abcam
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GABRG2 Antibody Blocking Peptide - LS-E98 from LifeSpan Bioscience
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GABRG2 Antibody Blocking Peptide - LS-E10693 from LifeSpan Bioscience
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GABRG2 Blocking Peptide - LS-E27346 from LifeSpan Bioscience
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GABRG2 Antibody Blocking Peptide - LS-E27347 from LifeSpan Bioscience
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GABRG2 Antibody Blocking Peptide - LS-E12649 from LifeSpan Bioscience
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GABRG2-Antibody-Center-Blocking-peptide - BP10189c from Abgent, a WuXi AppTec company
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GABRG2 Blocking Peptide - 33R-3267 from Fitzgerald
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GABRG2 Blocking Peptide - 33R-1384 from Fitzgerald
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Gaba A Receptor gamma 2 Peptide - AC21-2169-P from Abcore
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Gaba A Receptor gamma 2 Peptide - AC21-2170-P from Abcore
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GABRG2 Peptide - 42-569P from ProSci
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GABRG2 Peptide - 42-570P from ProSci
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GABRG2 fusion protein - Ag5489 from Proteintech Group
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GABRG2 fusion protein - ag5237 from Proteintech Group
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Recombinant Human GABRG2, His-tagged - GABRG2-13103H from Creative Biomart
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Recombinant Human GABRG2 - GABRG2-213H from Creative Biomart
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GABRG2, Peptide - MBS427290 from MyBioSource
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GABRG2 Peptide, Human - M34GP06027H from Creative Peptides
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Gamma-aminobutyric acid receptor subunit gamma-2 (GABRG2), Recombinant Protein - MBS956129 from MyBioSource
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GABRG2 Immunizing peptide - orb59823 from Biorbyt
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