| Gene Symbol |
PHKB
|
| Entrez Gene |
5257
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphorylase kinase, beta
|
| Other Description |
phosphorylase b kinase regulatory subunit beta|phosphorylase kinase beta-subunit|phosphorylase kinase subunit beta
|
| Swissprots |
Q8N4T5 Q93100
|
| Accessions |
CAA59333 CAA75422 EAW82700 EAW82701 Q93100 AK123692 BAG53937 AK293122 BAG56674 AK309226 BC033657 AAH33657 CR936710 DQ891354 ABM82280 X84908 CAA59332 XM_005255983 XP_005256040 XM_005255984 XP_005256041 XM_011523106 XP_011521408 XM_011523107 XP_011521409 NM_000293 NP_000284 NM_001031835 NP_001027005
|
| Function |
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
| Top Pathways |
Insulin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway
|
![Western Blot: Phosphorylase B Overexpression Lysate (Adult Normal) [NBP2-10607] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Phosphorylase B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6809_Phosphorylase%2520B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10607-img0001.jpg)
![Western Blot: Phosphorylase B Overexpression Lysate (Adult Normal) [NBP2-11145] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Phosphorylase B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1839_Phosphorylase%2520B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-11145-img0001.jpg)