Gene Symbol |
PHKB
|
Entrez Gene |
5257
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
phosphorylase kinase, beta
|
Other Description |
phosphorylase b kinase regulatory subunit beta|phosphorylase kinase beta-subunit|phosphorylase kinase subunit beta
|
Swissprots |
Q8N4T5 Q93100
|
Accessions |
CAA59333 CAA75422 EAW82700 EAW82701 Q93100 AK123692 BAG53937 AK293122 BAG56674 AK309226 BC033657 AAH33657 CR936710 DQ891354 ABM82280 X84908 CAA59332 XM_005255983 XP_005256040 XM_005255984 XP_005256041 XM_011523106 XP_011521408 XM_011523107 XP_011521409 NM_000293 NP_000284 NM_001031835 NP_001027005
|
Function |
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
|
Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
Top Pathways |
Insulin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway
|