Gene Symbol | PHKB |
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Entrez Gene | 5257 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | phosphorylase kinase, beta |
Other Description | phosphorylase b kinase regulatory subunit beta|phosphorylase kinase beta-subunit|phosphorylase kinase subunit beta |
Swissprots | Q8N4T5 Q93100 |
Accessions | CAA59333 CAA75422 EAW82700 EAW82701 Q93100 AK123692 BAG53937 AK293122 BAG56674 AK309226 BC033657 AAH33657 CR936710 DQ891354 ABM82280 X84908 CAA59332 XM_005255983 XP_005256040 XM_005255984 XP_005256041 XM_011523106 XP_011521408 XM_011523107 XP_011521409 NM_000293 NP_000284 NM_001031835 NP_001027005 |
Function | Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Top Pathways | Insulin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway |
PHKB CRISPR/Cas9 KO Plasmid (h) - sc-406832 from Santa Cruz Biotechnology
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PHKB HDR Plasmid (h) - sc-406832-HDR from Santa Cruz Biotechnology
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PHKB Double Nickase Plasmid (h) - sc-406832-NIC from Santa Cruz Biotechnology
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PHKB Double Nickase Plasmid (h2) - sc-406832-NIC-2 from Santa Cruz Biotechnology
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PHKB CRISPR Activation Plasmid (h) - sc-406832-ACT from Santa Cruz Biotechnology
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PHKB CRISPR Activation Plasmid (h2) - sc-406832-ACT-2 from Santa Cruz Biotechnology
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PHKB Lentiviral Activation Particles (h) - sc-406832-LAC from Santa Cruz Biotechnology
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PHKB Lentiviral Activation Particles (h2) - sc-406832-LAC-2 from Santa Cruz Biotechnology
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PHKB siRNA (h) - sc-93503 from Santa Cruz Biotechnology
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PHKB shRNA Plasmid (h) - sc-93503-SH from Santa Cruz Biotechnology
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PHKB shRNA (h) Lentiviral Particles - sc-93503-V from Santa Cruz Biotechnology
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Phosphorylase B RNAi - H00005257-R02 from Novus Biologicals
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MISSION® esiRNA - EHU072461 from Sigma-Aldrich
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MISSION® siRNA - SIHK1616 from Sigma-Aldrich
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MISSION® siRNA - SIHK1617 from Sigma-Aldrich
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MISSION® siRNA - SIHK1618 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16740 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16740 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08374 from Sigma-Aldrich
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PHKB siRNA (Human) - CRH3510 from Cohesion Biosciences
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shRNA set against Human PHKB (NM_000293.2) - SHH374892 from Creative biogene
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PHKB shRNA Plasmid (Human) - CHH3510 from Cohesion Biosciences
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