GPRC5A
| Gene Symbol | GPRC5A |
|---|---|
| Entrez Gene | 9052 |
| Alt Symbol | GPCR5A, PEIG-1, RAI3, RAIG1, TIG1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | G protein-coupled receptor, class C, group 5, member A |
| Other Description | G protein-coupled receptor, family C, group 5, member A|G-protein coupled receptor family C group 5 member A|TPA induced gene 1|orphan G-protein-coupling receptor PEIG-1|phorbol ester induced protein-1|retinoic acid induced 3|retinoic acid responsive|retinoic acid-induced gene 1 protein|retinoic acid-induced protein 3 |
| Swissprots | O95357 Q8NFJ5 B3KV45 |
| Accessions | EAW96289 Q8NFJ5 AF095448 AAC98506 AF506289 AAM77594 AI587426 AK001761 BAA91890 AK122672 BAG53657 AK172760 AK291171 BAF83860 BC003665 AAH03665 BE519991 NM_003979 NP_003970 |
| Function | Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. The comparable expression level in fetal lung and kidney with adult tissues suggests a possible role in embryonic development and maturation of these organs. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles. |
| Tissue Specificity | Expressed at high level in fetal and adult lung tissues. Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels. Not detectable in fetal heart, brain, and liver and adult heart, brain, liver, skeletal muscle, pancreas, spleen, thymus, and peripheral leukocytes. According to PubMed:10783259, expressed at low but detectable level in pancreas and heart. {ECO:0000269|PubMed:10783259, ECO:0000269|PubMed:10945465}. |
Human RAI3 full length protein - ab160313 from Abcam
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GPRC5A / RAI3 Antibody Blocking Peptide - LS-E28777 from LifeSpan Bioscience
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GPRC5A / RAI3 Antibody Blocking Peptide - LS-E28776 from LifeSpan Bioscience
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GPRC5A / RAI3 Antibody Blocking Peptide - LS-E28775 from LifeSpan Bioscience
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GPRC5A / RAI3 Antibody Blocking Peptide - LS-E8145 from LifeSpan Bioscience
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GPRC5A / RAI3 Antibody Blocking Peptide - LS-E28184 from LifeSpan Bioscience
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GPRC5A / RAI3 Antibody Blocking Peptide - LS-E28186 from LifeSpan Bioscience
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GPRC5A / RAI3 Antibody Blocking Peptide - LS-E28185 from LifeSpan Bioscience
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Recombinant Human GPRC5A/RAI3 Protein - H00009052-P01 from Novus Biologicals
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GPRC5A/RAI3 Peptide - P1847 from Novus Biologicals
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RAI3-Antibody-C-term-Blocking-Peptide - BP6239a from Abgent, a WuXi AppTec company
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PCQAP / MED15 blocking peptide - GTX88475-PEP from GeneTex
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GPCR5A Blocking Peptide - 33R-8711 from Fitzgerald
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RARRES1 protein (His tag) - 80R-2862 from Fitzgerald
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GPRC5A / RAI3 - H00009052-G01 from Acris Antibodies
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GPRC5A / RAI3 - H00009052-P01 from Acris Antibodies
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GPRC5A,RAI3 fusion protein - ag0311 from Proteintech Group
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Recombinant G Protein Coupled Receptor, Family C, Group 5, Member A (GPRC5A) - RPP745Hu01 from Uscn Life Science Inc.
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RAI3 (L179) Peptide - BS3199P from Bioworld Technology
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Recombinant G Protein Coupled Receptor, Family C, Group 5, Member A (GPRC5A) - RPP745Hu01 from Cloud-clone
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Recombinant Retinoic Acid Receptor Responder 1 (RARRES1) - RPH255Hu01 from Cloud-clone
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GPRC5A/RAI3 Recombinant Protein - H00009052-G01 from Novus Biologicals
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GPRC5A Blocking Peptide - abx161871 from Abbexa
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GPRC5A Protein - abx163118 from Abbexa
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GPRC5A / RAI3 - TP300118 from Acris Antibodies
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