GPRC5A

Gene Symbol GPRC5A
Entrez Gene 9052
Alt Symbol GPCR5A, PEIG-1, RAI3, RAIG1, TIG1
Species Human
Gene Type protein-coding
Description G protein-coupled receptor, class C, group 5, member A
Other Description G protein-coupled receptor, family C, group 5, member A|G-protein coupled receptor family C group 5 member A|TPA induced gene 1|orphan G-protein-coupling receptor PEIG-1|phorbol ester induced protein-1|retinoic acid induced 3|retinoic acid responsive|retinoic acid-induced gene 1 protein|retinoic acid-induced protein 3
Swissprots O95357 Q8NFJ5 B3KV45
Accessions EAW96289 Q8NFJ5 AF095448 AAC98506 AF506289 AAM77594 AI587426 AK001761 BAA91890 AK122672 BAG53657 AK172760 AK291171 BAF83860 BC003665 AAH03665 BE519991 NM_003979 NP_003970
Function Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. The comparable expression level in fetal lung and kidney with adult tissues suggests a possible role in embryonic development and maturation of these organs. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles.
Tissue Specificity Expressed at high level in fetal and adult lung tissues. Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels. Not detectable in fetal heart, brain, and liver and adult heart, brain, liver, skeletal muscle, pancreas, spleen, thymus, and peripheral leukocytes. According to PubMed:10783259, expressed at low but detectable level in pancreas and heart. {ECO:0000269|PubMed:10783259, ECO:0000269|PubMed:10945465}.

RAIG1 (D4S7D) XP ® Rabbit mAb - 12968 from Cell Signaling Technology

Prices $282.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4S7D
Western blot analysis of extracts from various cell lines using RAIG1 (D4S7D) XP ® Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8547 (lower)

RAIG1 Antibody - 5657 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from untransfected or human RAIG1-transfected 293T cells and untransfected MKN-45 cells using RAIG1 Antibody.

RAI3 (A-11) - sc-390263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RAI3 (A-11): sc-390263. Western blot analysis of RAI3 expression in non-transfected: sc-117752 (A) and human RAI3 transfected: sc-158912 (B) 293T whole cell lysates.

RAI3 (F-3) - sc-373824 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RAI3 (F-3): sc-373824. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic vesicles localization.

RAI3 (G-6) - sc-373825 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RAI3 (G-6): sc-373825. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic vesicles localization.

RAI3 (C-14) - sc-48665 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RAI3 (H-100) - sc-98884 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RAI3 (H-100): sc-98884. Western blot analysis of RAI3 expression in non-transfected (A) and human RAI3 transfected (B) whole cell lysates.

RAI3 (M-120) - sc-98885 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RAI3 (M-120): sc-98885. Western blot analysis of RAI3 expression in non-transfected (A) and human RAI3 transfected (B) whole cell lysates.

Anti-RAI3 antibody - C-terminal - ab140770 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin embedded Human brain neuron tissue labelling RAI3 with ab140770 at 10 µg/ml.

Anti-RAI3 antibody - C-terminal - ab71121 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RAI3 antibody - C-terminal (ab71121) at 1/100 dilution + A375 lysate at 12.5 µg

Anti-RAI3 antibody - N-terminal - ab155557 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RAI3 antibody - N-terminal (ab155557) at 1/1000 dilutionLane 1 : H1299 whole cell lysateLane 2 : HeLa whole cell lysateLane 3 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-GPRC5A / RAI3 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1221 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Uterus: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-GPRC5A / RAI3 Antibody (Transmembrane Domain) IHC-plus™ - LS-A3552 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPRC5A / RAI3 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPRC5A / RAI3 Antibody (aa343-357) - LS-C3183 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GPRC5A / RAI3 Antibody (Extracellular Domain) - LS-C9945 from LifeSpan Bioscience

Prices $485.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-GPRC5A / RAI3 Antibody (aa342-357) - LS-C147955 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-GPRC5A / RAI3 Antibody (aa284-300) - LS-C147909 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-GPRC5A / RAI3 Antibody (C-Terminus) - LS-C30514 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate

Anti-GPRC5A / RAI3 Antibody (N-Terminus) - LS-C153540 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GPRC5A / RAI3 Antibody (aa328-357) - LS-C100486 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of hRai3-W343 in T47D cell line lysates (35 ug/lane). RAI3 (arrow) was detected using the purified antibody.

Anti-GPRC5A / RAI3 Antibody (C-Terminus, AP) - LS-C226243 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPRC5A / RAI3 Antibody (C-Terminus, APC) - LS-C226244 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPRC5A / RAI3 Antibody (Leu179) - LS-C177410 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of RAI3 (L179) pAb in extracts from MCF7 cells.

Anti-GPRC5A / RAI3 Antibody (C-Terminus, Biotin) - LS-C226245 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPRC5A / RAI3 Antibody (C-Terminus, FITC) - LS-C226246 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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