GPRC5A

Gene Symbol GPRC5A
Entrez Gene 9052
Alt Symbol GPCR5A, PEIG-1, RAI3, RAIG1, TIG1
Species Human
Gene Type protein-coding
Description G protein-coupled receptor, class C, group 5, member A
Other Description G protein-coupled receptor, family C, group 5, member A|G-protein coupled receptor family C group 5 member A|TPA induced gene 1|orphan G-protein-coupling receptor PEIG-1|phorbol ester induced protein-1|retinoic acid induced 3|retinoic acid responsive|retinoic acid-induced gene 1 protein|retinoic acid-induced protein 3
Swissprots O95357 Q8NFJ5 B3KV45
Accessions EAW96289 Q8NFJ5 AF095448 AAC98506 AF506289 AAM77594 AI587426 AK001761 BAA91890 AK122672 BAG53657 AK172760 AK291171 BAF83860 BC003665 AAH03665 BE519991 NM_003979 NP_003970
Function Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. The comparable expression level in fetal lung and kidney with adult tissues suggests a possible role in embryonic development and maturation of these organs. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles.
Tissue Specificity Expressed at high level in fetal and adult lung tissues. Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels. Not detectable in fetal heart, brain, and liver and adult heart, brain, liver, skeletal muscle, pancreas, spleen, thymus, and peripheral leukocytes. According to PubMed:10783259, expressed at low but detectable level in pancreas and heart. {ECO:0000269|PubMed:10783259, ECO:0000269|PubMed:10945465}.

RAI3 CRISPR/Cas9 KO Plasmid (h) - sc-408795 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAI3 HDR Plasmid (h) - sc-408795-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAI3 Double Nickase Plasmid (h) - sc-408795-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAI3 Double Nickase Plasmid (h2) - sc-408795-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAI3 CRISPR Activation Plasmid (h) - sc-408795-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAI3 CRISPR Activation Plasmid (h2) - sc-408795-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAI3 Lentiviral Activation Particles (h) - sc-408795-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAI3 Lentiviral Activation Particles (h2) - sc-408795-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RAI3 siRNA (h) - sc-61440 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RAI3 shRNA Plasmid (h) - sc-61440-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RAI3 shRNA (h) Lentiviral Particles - sc-61440-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU015711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9630 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9630 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08209 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08209

GPRC5A siRNA (Human) - CRH5973 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPRC5A/RAI3 RNAi - H00009052-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GPRC5A - MBS8237026 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GPRC5A(NM_003979.3) - SHH101513 from Creative biogene

Category siRNA
Species Reactivities Human

GPRC5A shRNA Plasmid (Human) - CHH5973 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GPRC5A miRNA 3'UTR clone - MiUTR1H-04231 from Creative biogene

Species Reactivities Human
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