UAP1

Gene Symbol UAP1
Entrez Gene 6675
Alt Symbol AGX, AGX1, AGX2, SPAG2
Species Human
Gene Type protein-coding
Description UDP-N-acetylglucosamine pyrophosphorylase 1
Other Description UDP-N-acetylhexosamine pyrophosphorylase|antigen X|sperm associated antigen 2|sperm-associated antigen 2
Swissprots Q96GM2 Q5VTA9 Q5VTB0 Q5VTB1 B2R6R8 Q16222
Accessions EAW90710 EAW90711 EAW90712 Q16222 AB011004 BAA31202 AK312685 BAG35565 AW136085 BC009377 AAH09377 CB125476 S73498 AAB31210 XM_005245462 XP_005245519 XM_005245465 XP_005245522 XM_011509913 XP_011508215 XM_011509914 XP_011508216 XM_011509915 XP_011508217 NM_003115 NP_003106
Function Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
Subcellular Location Cytoplasm. Note=In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.
Tissue Specificity Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
Top Pathways Amino sugar and nucleotide sugar metabolism

UAP1 (N-16) - sc-244551 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

UAP1 (T-20) - sc-244552 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-UAP1 antibody - ab88360 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-UAP1 antibody (ab88360) at 1 µg/ml + Human liver lysate at 25 µgSecondaryGoat anti-Mouse IgG at 1/5000 dilution

Anti-UAP1 antibody - ab58211 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab58211 UAP1 antibody at 1ug/ml.

Anti-UAP1 antibody [EPR10259] - ab155287 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10259
All lanes : Anti-UAP1 antibody [EPR10259] (ab155287) at 1/1000 dilutionLane 1 : Human testis lysateLane 2 : Jurkat cell lysateLane 3 : A549 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-UAP1 Antibody (aa20-35) - LS-C144248 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-UAP1 Antibody (aa20-35) - LS-C148873 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-UAP1 Antibody (aa390-418, APC) - LS-C224572 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UAP1 Antibody (aa390-418, AP) - LS-C224570 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UAP1 Antibody (aa390-418, Biotin) - LS-C224573 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UAP1 Antibody (aa390-418, FITC) - LS-C224574 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UAP1 Antibody (aa390-418, PE) - LS-C224576 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UAP1 Antibody (aa390-418, Azide-free, HRP) - LS-C224577 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UAP1 Antibody (aa389-418) - LS-C326120 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UAP1 Antibody (C-Terminus) - LS-C135224 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UAP1 antibody LS-C135224 Western blot of Mouse Brain lysate. Antibody concentration 1 ug/ml.

Anti-UAP1 Antibody (aa400-449) - LS-C145696 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UAP1 antibody LS-C145696 Western blot of Small Intestine lysate. Antibody concentration 1 ug/ml.

Anti-UAP1 Antibody - LS-C192905 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of various cell lines, using UAP1 antibody.

Anti-UAP1 Antibody - LS-C331908 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using UAP1 antibody.

Anti-UAP1 Antibody (aa390-418) - LS-C157306 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UAP1 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The UAP1 antibody detected the UAP1 protein (arrow).

Anti-UAP1 Antibody (clone 3A9) - LS-C198250 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A9
Western Blot analysis of UAP1 expression in transfected 293T cell line by UAP1 monoclonal antibody (M01), clone 3A9.Lane 1: UAP1 transfected lysate (Predicted MW: 57.1 KDa).Lane 2: Non-transfected lysate.

Anti-UAP1 Antibody (aa53-473) - LS-C185548 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded ES-2 xenograft using UAP1 antibody at 1:500 dilution.

UAP1 Antibody - NBP1-89197 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UAP1 Antibody [NBP1-89197] - Analysis in human cell line U-251 MG.

UAP1 Antibody - NBP1-32823 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UAP1 Antibody [NBP1-32823] - Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE diluted at 1:3000

UAP1 Antibody - H00006675-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: UAP1 Antibody [H00006675-B01] - UAP1 MaxPab polyclonal antibody. Western Blot analysis of UAP1 expression in human liver.

UAP1 Antibody - H00006675-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: UAP1 Antibody [H00006675-B01P] - Analysis of UAP1 expression in human liver.
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