Gene Symbol | UAP1 |
---|---|
Entrez Gene | 6675 |
Alt Symbol | AGX, AGX1, AGX2, SPAG2 |
Species | Human |
Gene Type | protein-coding |
Description | UDP-N-acetylglucosamine pyrophosphorylase 1 |
Other Description | UDP-N-acetylhexosamine pyrophosphorylase|antigen X|sperm associated antigen 2|sperm-associated antigen 2 |
Swissprots | Q96GM2 Q5VTA9 Q5VTB0 Q5VTB1 B2R6R8 Q16222 |
Accessions | EAW90710 EAW90711 EAW90712 Q16222 AB011004 BAA31202 AK312685 BAG35565 AW136085 BC009377 AAH09377 CB125476 S73498 AAB31210 XM_005245462 XP_005245519 XM_005245465 XP_005245522 XM_011509913 XP_011508215 XM_011509914 XP_011508216 XM_011509915 XP_011508217 NM_003115 NP_003106 |
Function | Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P. |
Subcellular Location | Cytoplasm. Note=In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail. |
Tissue Specificity | Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver. |
Top Pathways | Amino sugar and nucleotide sugar metabolism |
Human UAP1 full length protein - ab159565 from Abcam
|
||||||||||
Human UAP1 protein fragment - ab159566 from Abcam
|
||||||||||
UAP1 Antibody Blocking Peptide - LS-E5307 from LifeSpan Bioscience
|
||||||||||
UAP1 Antibody Blocking Peptide - LS-E17792 from LifeSpan Bioscience
|
||||||||||
UAP1 Antibody Blocking Peptide - LS-E17573 from LifeSpan Bioscience
|
||||||||||
UAP1 Recombinant Protein - H00006675-P01 from Novus Biologicals
|
||||||||||
Recombinant Human UAP1 Protein - H00006675-Q01 from Novus Biologicals
|
||||||||||
UAP1-Antibody-C-term-Blocking-Peptide - BP17782b from Abgent, a WuXi AppTec company
|
||||||||||
UAP1 / AGX - H00006675-P01-10 from Acris Antibodies
|
||||||||||
UAP1 / AGX - H00006675-P01-25 from Acris Antibodies
|
||||||||||
UAP1 / AGX - H00006675-Q01-10 from Acris Antibodies
|
||||||||||
UAP1 / AGX - H00006675-Q01-25 from Acris Antibodies
|
||||||||||
UAP1 fusion protein - Ag9513 from Proteintech Group
|
||||||||||
UAP1 fusion protein - ag9371 from Proteintech Group
|
||||||||||
Recombinant Human UAP1, His-tagged - UAP1-3514H from Creative Biomart
|
||||||||||
Recombinant Human UDP-N-acetylhexosamine pyrophosphorylase(UAP1) - CSB-YP618067HU CSB-EP618067HU CSB-BP618067HU CSB-MP618067HU from Cusabio
|
||||||||||
UAP1 / AGX - TP303494 from Acris Antibodies
|
||||||||||
UAP1 Recombinant Protein Antigen - NBP1-89197PEP from Novus Biologicals
|
||||||||||
UAP1 Peptide, Human - M34GP16927H from Creative Peptides
|
||||||||||
Recombinant Human UDP-N-acetylhexosamine pyrophosphorylase(UAP1) - RPC20419 from Biomatik
|
||||||||||
Recombinant Human UDP-N-acetylhexosamine pyrophosphorylase(UAP1) - AP74128 from Signalway Antibody
|
||||||||||
Recombinant Human UDP-N-acetylhexosamine pyrophosphorylase(UAP1) - AP74621 from Signalway Antibody
|
||||||||||
UAP1 Recombinant Protein (Human) (OPCA04552) - OPCA04552 from Aviva Systems Biology
|
||||||||||
UAP1 Recombinant Protein (Human) (OPCA04558) - OPCA04558 from Aviva Systems Biology
|
||||||||||
Recombinant Human UDP-N-acetylhexosamine pyrophosphorylase (UAP1) - RPC25359 from Biomatik
|