PLB1

Gene Symbol PLB1
Entrez Gene 151056
Alt Symbol PLB, PLB/LIP, hPLB
Species Human
Gene Type protein-coding
Description phospholipase B1
Other Description lysophospholipase|phospholipase A2|phospholipase B|phospholipase B/lipase|phospholipase B1, membrane-associated
Swissprots Q96DP9 Q53S03 Q6P1J6 Q8IUP7 A8KAX2
Accessions AAY24081 AAY24082 EAX00532 EAX00533 EAX00534 EAX00535 EAX00536 Q6P1J6 AK055428 BAB70920 BC042674 AAH42674 BC065041 AAH65041 BC150633 AAI50634 BC153864 AAI53865 BX109719 XM_011532579 XP_011530881 XM_011532580 XP_011530882 XM_011532581 XP_011530883 XM_011532582 XP_011530884 XM_011532583 XP_011530885 XM_011532584 XP_011530886 XM_011532585 XP_011530887 XM_011532586 XP_011530888 XM_011532587 XP_011530889 XM_011532588 XP_011530890 XM_011532589 XP_011530891 XM_011532590 XP_011530892 XM_011532591 XP_011530893 XM_011532592 XP_011530894 XM_011532593 XP_011530895 XM_011532594 XP_011530896 XM_011532595 XP_011530897 XM_011532596 XP_011530898 XM_011532597 XP_011530899 XM_011532598 XP_011530900 XM_011532599 XP_011530901 XM_011532600 XP_011530902 XM_011532601 XP_011530903 XM_011532602 XP_011530904 XM_011532603 XP_011530905 XM_011532604 XP_011530906 XM_011532605 XP_011530907 XM_011532606 XP_011530908 XM_011532607 XP_011530909 XM_011532608 XP_011530910 XM_011532609 XP_011530911 XM_011532610 XP_011530912 XM_011532611 XP_011530913 XM_011532612 XP_011530914 XR_939661 XR_939662 XR_939663 XR_939664 XR_939665 XR_939666 XR_939667 NM_001170585 NP_001164056 NM_153021 NP_694566
Function Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity). {ECO:0000250}.
Subcellular Location Apical cell membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. Note=Present in the intestinal brush border membranes. {ECO:0000250}.
Tissue Specificity Expressed in the epidermis (at protein level). {ECO:0000269|PubMed:12150957}.
Top Pathways Vitamin digestion and absorption, Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism, alpha-Linolenic acid metabolism

PLB CRISPR/Cas9 KO Plasmid (h) - sc-414696 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLB HDR Plasmid (h) - sc-414696-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLB Double Nickase Plasmid (h) - sc-414696-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLB Double Nickase Plasmid (h2) - sc-414696-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLB CRISPR Activation Plasmid (h) - sc-414696-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLB CRISPR Activation Plasmid (h2) - sc-414696-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLB Lentiviral Activation Particles (h) - sc-414696-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLB Lentiviral Activation Particles (h2) - sc-414696-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PLB siRNA (h) - sc-95008 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLB shRNA Plasmid (h) - sc-95008-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLB shRNA (h) Lentiviral Particles - sc-95008-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU072701 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16917 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16917 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLB1 siRNA (Human) - CRJ5682 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLB1 (NM_153021.4) - SHH377072 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLB1 siRNA - orb276183 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLB1 shRNA Plasmid (Human) - CHJ5682 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLB1 miRNA 3'UTR clone - MiUTR3H-11072 from Creative biogene

Species Reactivities Human
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