PLB1

Gene Symbol PLB1
Entrez Gene 151056
Alt Symbol PLB, PLB/LIP, hPLB
Species Human
Gene Type protein-coding
Description phospholipase B1
Other Description lysophospholipase|phospholipase A2|phospholipase B|phospholipase B/lipase|phospholipase B1, membrane-associated
Swissprots Q96DP9 Q53S03 Q6P1J6 Q8IUP7 A8KAX2
Accessions AAY24081 AAY24082 EAX00532 EAX00533 EAX00534 EAX00535 EAX00536 Q6P1J6 AK055428 BAB70920 BC042674 AAH42674 BC065041 AAH65041 BC150633 AAI50634 BC153864 AAI53865 BX109719 XM_011532579 XP_011530881 XM_011532580 XP_011530882 XM_011532581 XP_011530883 XM_011532582 XP_011530884 XM_011532583 XP_011530885 XM_011532584 XP_011530886 XM_011532585 XP_011530887 XM_011532586 XP_011530888 XM_011532587 XP_011530889 XM_011532588 XP_011530890 XM_011532589 XP_011530891 XM_011532590 XP_011530892 XM_011532591 XP_011530893 XM_011532592 XP_011530894 XM_011532593 XP_011530895 XM_011532594 XP_011530896 XM_011532595 XP_011530897 XM_011532596 XP_011530898 XM_011532597 XP_011530899 XM_011532598 XP_011530900 XM_011532599 XP_011530901 XM_011532600 XP_011530902 XM_011532601 XP_011530903 XM_011532602 XP_011530904 XM_011532603 XP_011530905 XM_011532604 XP_011530906 XM_011532605 XP_011530907 XM_011532606 XP_011530908 XM_011532607 XP_011530909 XM_011532608 XP_011530910 XM_011532609 XP_011530911 XM_011532610 XP_011530912 XM_011532611 XP_011530913 XM_011532612 XP_011530914 XR_939661 XR_939662 XR_939663 XR_939664 XR_939665 XR_939666 XR_939667 NM_001170585 NP_001164056 NM_153021 NP_694566
Function Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity). {ECO:0000250}.
Subcellular Location Apical cell membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. Note=Present in the intestinal brush border membranes. {ECO:0000250}.
Tissue Specificity Expressed in the epidermis (at protein level). {ECO:0000269|PubMed:12150957}.
Top Pathways Vitamin digestion and absorption, Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism, alpha-Linolenic acid metabolism

PLB (I-17) - sc-324937 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PLB (T-17) - sc-324935 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Phospholipase A2 (phospho S505) antibody - ab53105 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Phospholipase A2 (phospho S505) antibody (ab53105) at 1/300 dilutionLane 1 : extracts from HeLa cells treated with TNF-a (20ng/ml, 30mins)Lane 2 : extracts from HeLa cells treated with TNF-a (20ng/ml, 30mins) with immunising peptide

Anti-Phospholipase A2 antibody - ab58375 from Abcam

Prices $398.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Phospholipase A2 antibody (ab58375) at 1/500 dilutionLane 1 : HeLa cell extracts treated with TNF alpha (20ng/ml, 30mins)Lane 2 : HeLa cell extracts treated with TNF alpha (20ng/ml, 30mins) with immunising peptide

Anti-Phospholipase A2 antibody - ab135825 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Phospholipase A2 antibody (ab135825) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

Anti-Phospholipase A2 antibody - ab73406 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Phospholipase A2 antibody (ab73406) at 1 µg/ml + HeLa Whole Cell Lysate - Bleomycin Treated (40U/ml) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Phospholipase A2 antibody - ab139388 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Phospholipase A2 antibody (ab139388) at 1/500 dilutionLane 1 : HeLa cell lysate treated with TNF alpha at 20 ng/ml for 30 minutesLane 2 : HeLa cell lysate treated with TNF alpha at 20 ng/ml for 30 minutes, and also treated with the synthesized peptide

Anti-Phospholipase A2 antibody - ab124230 from Abcam

Prices $378.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-Phospholipase A2 antibody (ab124230) at 3 µg/ml + HeLa cell lysate at 35 µg

Anti-Phospholipase A2 antibody - ab104252 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Phospholipase A2 antibody (ab104252) at 1 µg + HeLa cell lysate at 35 µg

Anti-Phospholipase A2 antibody - ab55648 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab55648 Phospholipase A2 antibody at 1ug/ml.

Anti-PLB1 antibody - ab92915 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PLB1 antibody (ab92915) at 1/500 dilution + Human colon lysate at 50 µg

Anti-PLB1 antibody [1B3] - ab180389 from Abcam

Prices $357.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B3
All lanes : Anti-PLB1 antibody [1B3] (ab180389) at 1/4000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY PLB1 cDNALysates/proteins at 5 µg per lane.

Anti-PLB1 Antibody (clone 1B3) - LS-C340616 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLB1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLB1.

Anti-PLB1 Antibody (clone 1D3) - LS-C338223 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLB1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PLB1.

Phospholipase B1 Antibody - NBP1-92267 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Phospholipase B1 Antibody [NBP1-92267] - Staining of human cell line U-2 OS shows positivity in cytoplasm.

Phospholipase B1 Antibody - H00151056-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Phospholipase B1 Antibody [H00151056-B01P] - Analysis of PLB1 expression in transfected 293T cell line by PLB1 polyclonal antibody. Lane 1: PLB1 transfected lysate(46.53 KDa). Lane 2: Non-transfected lysate.

Anti-PLB1 antibody produced in mouse - SAB1408383 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PLB1: <B>Cat. No. SAB1408383</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~163.1 kDa using human colon lysate.

Anti-PLB1 antibody produced in rabbit - HPA014045 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PLB1: <B>Cat. No. HPA014045</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cerebellum shows strong cytoplasmic positivity in purkinje cells.

Anti-PLB1 antibody produced in mouse - SAB1408917 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PLB1: <B>Cat. No. SAB1408917</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~46.5 kDa using PLB1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Phospholipase B1 / PLB1 antibody - H00151056-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Phospholipase B1 / PLB1 antibody - H00151056-B02P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
PLB1 MaxPab polyclonal antibody. Western Blot analysis of PLB1 expression in human colon.

Monoclonal Antibody to Phospholipase B (PLB) - MAC048Hu22 from Uscn Life Science Inc.

Host Mouse
Clonality Monoclonal

Polyclonal Antibody to Phospholipase B (PLB) - PAC048Hu01 from Uscn Life Science Inc.

Host Rabbit
Clonality Polyclonal

Anti-PLB1 monoclonal antibody, clone 2C4 - DCABH-6781 from Creative Diagnostics

Host Mouse
Clonality Monoclonal
Clone 2C4

PLB1, Polyclonal Antibody - MBS641392 from MyBioSource

Prices $580.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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