EPHB2

Gene Symbol	EPHB2
Entrez Gene	2048
Alt Symbol	CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5
Species	Human
Gene Type	protein-coding
Description	EPH receptor B2
Other Description	EPH-like kinase 5|developmentally-regulated Eph-related tyrosine kinase|elk-related tyrosine kinase|eph tyrosine kinase 3|ephrin type-B receptor 2|protein-tyrosine kinase HEK5|renal carcinoma antigen NY-REN-47|tyrosine-protein kinase TYRO5|tyrosine-protein kinase receptor EPH-3
Swissprots	Q5T0U7 O43477 Q5T0U8 Q5T0U6 P29323
Accessions	CAA41981 CAD83767 CAT16948 EAW95022 EAW95023 EAW95024 EAW95025 EAW95026 P29323 AB210018 BAE06100 AF025304 AAB94602 AK298898 BAG61009 AK299701 BAG61602 AL530874 BC007903 BC018763 BC041017 BC067861 AAH67861 BC146296 AAI46297 BQ641281 D14717 BAA03537 D31661 BAA06506 D37827 BAA07073 HM437237 ADN43068 L36643 AAA74244 L41939 AAA99310 XM_006710441 XP_006710504 XM_006710442 XP_006710505 XM_011540976 XP_011539278 NM_004442 NP_004433 NM_017449 NP_059145
Function	Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation. Controls other aspects of developm
Subcellular Location	Cell membrane; Single-pass type I membrane protein. Cell projection, axon {ECO:0000250}. Cell projection, dendrite {ECO:0000250}.
Tissue Specificity	Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EPHB2 / EPH Receptor B2 ELISA Kit (Cell-Based ELISA) - LS-F1969 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.625-40 ng/ml

Phosphotyrosine EPHB2 / Ephrin Type-B Receptor 2 ELISA Kit - RAB0950 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Human ERK ELISA Kit - abx054511 from Abbexa Category ELISA Kit Sensitivity 0.03 ng/ml Range 0.1 ng/ml - 5 ng/ml

Ephrin type-B receptor 2 (EPHB2), Human, ELISA Kit - CSB-EL007730HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

ERK (Extracellular Signal Regulated Kinase), Human, ELISA Kit - E-EL-H2085 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t

F-actin-capping protein subunit beta (CAPZB), Human, ELISA Kit - CSB-EL004514HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

ERK (Extracellular Signal Regulated Kinase), Rabbit, ELISA Kit - E-EL-RB1504 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ERK (Extracellular Signal Regulated Kinase), Chicken, ELISA Kit - E-EL-Ch0089 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ERK (Extracellular Signal Regulated Kinase), Pig, ELISA Kit - E-EL-P0447 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ERK (Extracellular Signal Regulated Kinase), Guinea Pig, ELISA Kit - E-EL-GP1229 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

ERK (Extracellular Signal Regulated Kinase), Monkey, ELISA Kit - E-EL-MK2109 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

Phospho-ERK/JNK/P38α ELISA - PEL-MAPK-SK from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human ERK ELISA Kit - HE0178 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ERK ELISA Kit - AE0178 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

EPH receptor B2, ELISA Kit - MBS913951 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.156 ng/ml. Range 0.625 ng/ml-40 ng/ml.

EPHB2 Colorimetric Cell-Based ELISA Kit - CB5240 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Human ERK (Extracellular Signal Regulated Kinase) ELISA Kit - E-EL-H2085 from Elabscience Category ELISA Kit Range ~0

ERK, ELISA Kit - MBS2502264 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ERK, ELISA Kit - MBS2505598 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ERK, ELISA Kit - MBS2510215 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ERK - MBS2509289 from MyBioSource Category ELISA Kit Prices $475.00, $575.00 Sizes 48 strip wells, 96 strip wells

ERK, ELISA Kit - MBS2504431 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ERK, ELISA Kit - MBS2507762 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Ephrin type-B receptor 2(EPHB2) ELISA kit - CSB-EL007730HU from Cusabio Category ELISA Kit Sensitivity 0.156 ng/ml Range 0.625 ng/ml-40 ng/ml

Human ERK (Extracellular Signal Regulated Kinase) ELISA Kit - E-EL-H2085 from Iwai North America Inc. Category ELISA Kit Prices $649.00 Sizes 1 kit Sensitivity N/A

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