CCP110

Gene Symbol CCP110
Entrez Gene 9738
Alt Symbol CP110, Cep110
Species Human
Gene Type protein-coding
Description centriolar coiled coil protein 110kDa
Other Description centriolar coiled-coil protein of 110 kDa|centrosomal protein CP110|centrosomal protein of 110 kDa
Swissprots Q68DV9 O43335 B7WP23 Q8NE13 O43303
Accessions AAC05804 EAW50287 EAW50288 O43303 AB007879 BAA24849 AK300426 BAG62153 AK309196 BC030223 BC034140 BC036654 AAH36654 BP360952 BQ632514 BY798911 CB066937 CN307903 CN307908 CR749255 CAH18111 DA250590 DA370828 DB504255 DQ891266 ABM82192 DQ894454 ABM85380 XM_005255719 XP_005255776 XM_011545991 XP_011544293 XM_011545992 XP_011544294 XM_011545993 XP_011544295 NM_001199022 NP_001185951 NM_014711 NP_055526
Function Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2. {ECO:0000269|PubMed:12361598, ECO:0000269|PubMed:16760425, ECO:0000269|PubMed:17681131, ECO:0000269|PubMed:17719545, ECO:0000269|PubMed:23486064}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:12361598, ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:16760425, ECO:0000269|PubMed:17681131, ECO:0000269|PubMed:17719545, ECO:0000269|PubMed:20596027, ECO:0000269|PubMed:21620453}. Note=Recruited early and then associates with the growing distal tips. Recruited to the mother centriole by KIF24. Removed from centrioles by TTBK2, leading to initiation of ciliogenesis.
Tissue Specificity Highly expressed in testis. Detected at intermediate levels in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:12361598}.

CP110 Antibody - 12140 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cells lines using CP110 Antibody.

CP110 (N-14) - sc-136629 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

CP110 (Q-12) - sc-136630 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-CP110 antibody - ab99337 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CP110 antibody (ab99337) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-CP110 antibody - ab99338 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CP110 antibody (ab99338) at 0.04 µg/mlLane 1 : Hela whole cell lysate at 50 µgLane 2 : Hela whole cell lysate at 15 µgLane 3 : Hela whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-CP110 antibody - ab91415 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CP110 antibody (ab91415) at 1/100 dilution + HL-60 cell line lysates at 35 µg

Anti-CP110 antibody - ab169828 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

Anti-CP110 antibody - C-terminal - ab189885 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-CP110 antibody - C-terminal (ab189885) at 1 µg/mlLane 2 : Anti-CP110 antibody - C-terminal (ab189885) at 2 µg/mlLane 1 : Human colon tissue lysateLane 2 : Human colon tissue lysate

Anti-CCP110 Antibody (aa8-19) - LS-C186469 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
CCP110 antibody (1 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CCP110 Antibody - LS-C346073 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot blot of extracts of HeLa cell line, using CCP110 antibody.

Anti-CCP110 Antibody (C-Terminus) IHC-plus™ - LS-B8825 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CCP110 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CCP110 Antibody (aa575-625) - LS-C288151 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CCP110 Antibody (aa962-1012) - LS-C288152 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CCP110 Antibody (aa850-900) - LS-C291305 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CEP110 Antibody - NB100-61066 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CEP110 Antibody [NB100-61066] - Detection of Human CEP110 on HeLa whole cell lysate using NB100-61066. CEP110 was also immunoprecipitated, albeit less efficiently, by rabbit anti-CEP110 antibody NB100-61067.

CCP110 Antibody - NBP2-13073 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: CCP110 Antibody [NBP2-13073] - Staining of human cell line U-251 MG shows positivity in centrosome. Antibody staining is shown in green.

CEP110 Antibody - NB100-61067 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CCP110 Antibody - NBP2-26118 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: CCP110 Antibody [NBP2-26118] - Staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

CP110 Polyclonal Antibody - bs-9307R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CP110 (N-terminal) antibody produced in goat - SAB2502023 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CP110 (N-terminal) <B>Cat. No. SAB2502023</B>: Immunoblotting (1 μg/mL) staining of Human Testis lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CCP110 antibody produced in rabbit - HPA039402 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AC012621.2: <B>Cat. No. HPA039402</B>: Immunohistochemical staining of human testis shows strong granular cytoplasmic positivity in cells in seminiferus ducts and leydig cells.

Anti-CCP110 antibody produced in rabbit - SAB3500793 from Sigma-Aldrich

Prices $341.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>CCP110 Antibody: <B>Cat. No. SAB3500793</B>: Western blot analysis of CCP110 in Human colon tissue lysate with CCP110 antibody at (A) 1 and (B) 2 μg/mL.

CP110-Antibody-N-Term - AF3694a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3694a (1 µg/ml) staining of Human Testis lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

CP110 antibody - GTX87065 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

CCP110 Antibody (OAAF03463) - OAAF03463 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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