BID

Gene Symbol BID
Entrez Gene 637
Alt Symbol FP497
Species Human
Gene Type protein-coding
Description BH3 interacting domain death agonist
Other Description BH3-interacting domain death agonist|BID isoform ES(1b)|BID isoform L(2)|BID isoform Si6|Human BID coding sequence|apoptic death agonist|desmocollin type 4|p22 BID
Swissprots Q7Z4M9 Q71T04 P55957 Q8IY86 Q549M7
Accessions AAP50259 CAG17894 EAW57770 EAW57771 EAW57772 EAW57773 EAW57774 P55957 AF042083 AAC34365 AF087891 AAP97190 AF250233 AAO32633 AF370380 AAQ15216 AK094795 BAG52933 AK313729 BAG36471 AY005151 AAF89091 BC005884 BC009197 AAH09197 BC022072 AAH22072 BC033634 AAH33634 BC036364 AAH36364 BM561391 BM842561 BQ068464 CN277529 CR407603 CAG28531 CR456389 CAG30275 CU012947 CAK54378 CU013235 CAK54677 D89803 BAF79673 DA007047 DA158889 DA274603 DB167767 EU446512 ABZ92041 EU447348 ACA61804 EU678292 ACD47106 EU678293 ACD47107 EU678294 ACD47108 NM_001196 NP_001187 NM_001244567 NP_001231496 NM_001244569 NP_001231498 NM_001244570 NP_001231499 NM_001244572 NP_001231501 NM_197966 NP_932070 NM_197967 NP_932071
Function The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2. {ECO:0000250, ECO:0000269|PubMed:14583606}.
Subcellular Location Isoform 3: Cytoplasm.
Tissue Specificity Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level). {ECO:0000269|PubMed:14583606}.
Top Pathways Sphingolipid signaling pathway, Apoptosis, Non-alcoholic fatty liver disease (NAFLD), Tuberculosis, Amyotrophic lateral sclerosis (ALS)

BID (7A3) Mouse mAb (Human Specific) - 2006 from Cell Signaling Technology

Host Mouse
Clonality Monoclonal
Clone 7A3
Western blot analysis of extracts from Jurkat, A431 and HeLa cells, using BID (7A3) Mouse mAb (Human Specific).

Bid (3C5) Mouse mAb - 8762 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 3C5
Western blot analysis of extracts from various cell lines using Bid (3C5) Mouse mAb.

BID Antibody (Human Specific) - 2002 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Jurkat cells, untreated or etoposide-treated (25 µM), and RS4;11 cells, untreated or okadaic acid-treated (1 µM), using BID Antibody (Human Specific).

BID (N-19) - sc-6539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BID (N-19): sc-6539. Western blot analysis of BID expression in Jurkat (A) and IMR-32 (B) whole cell lysates.

BID (B-3) - sc-373939 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BID (B-3): sc-373939. Western blot analysis of BID expression in 293T (A) and HeLa (B) whole cell lysates.

BID (C-20) - sc-6538 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BID (C-20): sc-6538. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

BID (FL-195) - sc-11423 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BID siRNA (h): sc-29800. Western blot analysis of BID expression in non-transfected control (A) and BID siRNA transfected (B) HeLa cells. Blot probed with BID (FL-195): sc-11423. GAPDH (FL-335): sc-25778 used as specificity and loading control.

BID (5C9) - sc-56025 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
BID (5C9): sc-56025. Western blot analysis of BID expression in etoposide-treated HeLa (A), DU 145 (B), PC-3 (C) and MCF7 (D) whole cell lysates.

cleaved BID (h71) - sc-34325 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cleaved BID (h71): sc-34325. Western blot analysis of BID expression in non-transfected: sc-117752 (A) and human BID transfected: sc-115264 (B) 293T whole cell lysates.

p-BID (Ser 65) - sc-130180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-BID (Ser 65): sc-130180. Immunoperoxidase staining of formalin fixed, paraffin-embedded human hepatocarcinoma tissue showing cytoplasmic staining.

Anti-Bid (phospho S65) antibody - ab59975 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Bid (phospho S65) antibody (ab59975) at 1/100 dilution + Jurkat cell lysate

Anti-Bid (phospho S78) antibody - ab59174 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded human brain tissue using ab59174 at 1/50-1/100 dilution. Samples treated with (+) or without (-) phospho peptide.

Anti-Bid antibody - ab63541 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Bid antibody (ab63541) at 1/500 dilutionLane 1 : Extracts from Jurkat cells (5ug) treated with H2O2 (100uM, 30mins)Lane 2 : Extracts from Jurkat cells (5ug) treated with etoposide (25uM, 60 mins)Lane 3 : Extracts from Jurkat cells (5ug) treated with H2O2 (100uM, 30mins) and etoposide (25uM, 60 mins) with immunizing non-phosphopeptide at 5 µg

Anti-Bid antibody - ab2388 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Bid in Jurkat cells treated with anti-Fas for 6 hours.

Anti-Bid antibody - ab14436 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma tissue labelling Bid with ab14436 at 1/1000 (1µg/ml). Detection: DAB.

Anti-Bid antibody - ab31273 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Bid antibody (ab31273) at 0.1 µg/ml + Human Fibroblast A431 lysate (35µg protein in RIPA buffer)

Anti-Bid antibody - ab14437 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Bid antibody (ab14437) at 1 µg/ml + Whole Hela cell lysate at 40 µg

Anti-Bid antibody - ab137752 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Bid antibody (ab137752) at 1/1000 dilution + A431 cell lysate at 30 µg

Anti-Bid antibody - ab77815 from Abcam

Prices $373.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Bid antibody [1H11] - ab109796 from Abcam

Prices $376.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone 1H11
All lanes : Anti-Bid antibody [1H11] (ab109796) at 2 µg/mlLane 1 : Jurkat cell lysateLane 2 : Mouse splenocytes lysatePerformed under reducing conditions.

Anti-Bid antibody [2H9] - ab180394 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2H9
All lanes : Anti-Bid antibody [2H9] (ab180394) at 1/400 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY Bid cDNALysates/proteins at 5 µg per lane.

Anti-Bid antibody [3C5] - ab114051 from Abcam

Prices $395.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3C5
ab114051, at a 1/200 dilution, staining Bid in paraffin embedded Human prostate tissue by Immunohistochemistry, with DAB staining.

Anti-Bid antibody [3C5] - ab130182 from Abcam

Host Mouse
Clonality Monoclonal
Clone 3C5
All lanes : Anti-Bid antibody [3C5] (ab130182) at 1/500 dilutionLane 1 : Hela cell lysateLane 2 : A431 cell lysateLane 3 : Jurkat cell lysateLane 4 : A549 cell lysateLane 5 : HepG2 cell lysateLane 6 : HEK293 cell lysate

Anti-Bid antibody [4A1] - ab170154 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4A1
Immunofluorescent analysis of COS7 cells transiently transfected with pCMV6-ENTRY Bid, labeling Bid with ab170154 at 1/100 dilution.

Anti-Bid antibody [4D3] - ab81612 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4D3
Anti-Bid antibody [4D3] (ab81612) at 1/1000 dilution + Jurkat lysates at 20 µgSecondaryGoat anti-mouse secondary antibody conjugated to HRP developed using the ECL technique
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