Gene Symbol | TOX3 |
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Entrez Gene | 27324 |
Alt Symbol | CAGF9, TNRC9 |
Species | Human |
Gene Type | protein-coding |
Description | TOX high mobility group box family member 3 |
Other Description | CAG trinucleotide repeat-containing gene F9 protein|trinucleotide repeat containing 9|trinucleotide repeat-containing gene 9 protein |
Swissprots | B4DRD0 B5MCW4 O15405 |
Accessions | EAW82787 O15405 AK025084 AK027006 AK095095 AK299202 BAG61242 BC167799 AAI67799 BE501808 U80736 AAB91435 XM_005255892 XP_005255949 XM_005255893 XP_005255950 XM_011523002 XP_011521304 NM_001080430 NP_001073899 NM_001146188 NP_001139660 |
Function | Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region. {ECO:0000269|PubMed:21172805}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed mainly in epithelial cells. Expressed in the central nervous system (CNS), in the ileum and within the brain in the frontal and occipital lobe. {ECO:0000269|PubMed:21172805}. |
TOX3 (Q-15) - sc-165762 from Santa Cruz Biotechnology
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Anti-TOX3 antibody - ab175129 from Abcam
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Anti-TOX3 antibody - ab77432 from Abcam
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Anti-TOX3 antibody [EPR6173(2)(B)] - ab151548 from Abcam
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Anti-TNRC9 / TOX3 Antibody (aa10-21) - LS-C61798 from LifeSpan Bioscience
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Anti-TNRC9 / TOX3 Antibody (aa214-242, APC) - LS-C218063 from LifeSpan Bioscience
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Anti-TNRC9 / TOX3 Antibody (aa214-242, AP) - LS-C218062 from LifeSpan Bioscience
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Anti-TNRC9 / TOX3 Antibody (aa214-242, Biotin) - LS-C218064 from LifeSpan Bioscience
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Anti-TNRC9 / TOX3 Antibody (aa214-242, Azide-free, HRP) - LS-C218065 from LifeSpan Bioscience
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Anti-TNRC9 / TOX3 Antibody (aa214-242, FITC) - LS-C218066 from LifeSpan Bioscience
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Anti-TNRC9 / TOX3 Antibody (aa214-242, PE) - LS-C218067 from LifeSpan Bioscience
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Anti-TNRC9 / TOX3 Antibody (aa221-250) - LS-C325875 from LifeSpan Bioscience
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Anti-TNRC9 / TOX3 Antibody (N-Terminus) - LS-C345439 from LifeSpan Bioscience
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Anti-TNRC9 / TOX3 Antibody (aa214-242) - LS-C160124 from LifeSpan Bioscience
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TOX3 Antibody - NBP1-86676 from Novus Biologicals
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TOX3 Antibody - NBP1-00247 from Novus Biologicals
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Anti-TOX3 antibody produced in rabbit - HPA040376 from Sigma-Aldrich
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TOX3 Antibody - N-terminal region (ARP45744_P050) - ARP45744_P050 from Aviva Systems Biology
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TOX3 Antibody - middle region (OAAB02231) - OAAB02231 from Aviva Systems Biology
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TOX3-Antibody-Center - AP4814c from Abgent, a WuXi AppTec company
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TOX3-Antibody-N-Term - AF2614a from Abgent, a WuXi AppTec company
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TOX3 Antibody (OAEB00078) - OAEB00078 from Aviva Systems Biology
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Anti-TOX3 Antibody - AC11-0455 from Abcore
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Anti-TOX3 Antibody - AC21-1278 from Abcore
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Anti-TOX3 Antibody (AMCA) - AC21-1278-01 from Abcore
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