CCAR1

Gene Symbol CCAR1
Entrez Gene 55749
Alt Symbol -
Species Human
Gene Type protein-coding
Description cell division cycle and apoptosis regulator 1
Other Description cell cycle and apoptosis regulatory protein 1|cell division cycle and apoptosis regulator protein 1|death inducer with SAP domain
Swissprots A1L4P7 A8K9D4 Q9NVQ0 Q5VUP6 Q8IX12 Q9NWM6 Q5EBM3 Q9NVA7 Q6PIZ0 B4DNP8 A0JLT7 Q6X935 Q32NE3 B4DRK8 Q9H8N4
Accessions CBX47496 EAW54300 EAW54301 EAW54302 Q8IX12 AF465616 AAO17319 AK000741 BAA91354 AK001701 BAA91847 AK023438 BAB14574 AK122871 AK292649 BAF85338 AK298004 BAG60310 AK299307 BAG61320 AK307550 AK307671 AK307704 AY249140 AAP82002 BC015475 AAH15475 BC026036 AAH26036 BC058846 BC089420 AAH89420 BC108682 AAI08683 BC130626 AAI30627 BC132725 AAI32726 BC144118 BM786237 BM905703 BU181074 BU617955 BX647943 CB136079 DA511293 DB636717 NM_001282959 NP_001269888 NM_001282960 NP_001269889 NM_018237 NP_060707 NR_104262
Function Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation. {ECO:0000250, ECO:0000269|PubMed:12816952}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000269|PubMed:12816952}.
Tissue Specificity Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors. {ECO:0000269|PubMed:12816952}.

CARP-1 (C-20) - sc-69263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CARP-1 (C-20): sc-69263. Western blot analysis of CARP-1 expression in HeLa nuclear extract.

Anti-DIS antibody - ab183909 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of methanol-fixed A431 cells labeling DIS with ab183909 at 1/500 dilution. Blue: Hoechst 33342 staining. 

Anti-DIS antibody - ab70244 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DIS antibody (ab70244) at 1 µg/mlLane 1 : Nuclear extract from HeLa cells at 15 µgLane 2 : Nuclear extract from HeLa cells at 45 µg

Anti-DIS / CCAR1 Antibody (aa700-750) - LS-C78022 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DIS / CCAR1 Antibody (aa1-50) - LS-C78077 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS / CCAR1 Antibody (C-Terminus) - LS-C78079 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS / CCAR1 Antibody (aa700-750) - LS-C188044 from LifeSpan Bioscience

Prices $520.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DIS / CCAR1 Antibody (aa700-750) - LS-C285992 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS / CCAR1 Antibody (C-Terminus) - LS-C285999 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS / CCAR1 Antibody (aa100-150) - LS-C285998 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DIS / CCAR1 Antibody - LS-C335654 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using CCAR1 antibody.

Anti-DIS / CCAR1 Antibody (aa901-912) - LS-C108942 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
CCAR1 antibody (1 ug/ml) staining of Rat Skeletal Muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-DIS / CCAR1 Antibody (aa1-50) - LS-C286363 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse CCAR1 by Immunohistochemistry. Sample: FFPE section of mouse squamous cell carcinoma. Antibody: Affinity purified rabbit anti-CCAR1 used at a dilution of 1:250. Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1:100.

Anti-DIS / CCAR1 Antibody (aa1-50) - LS-C287327 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse CCAR1 by Immunohistochemistry. Sample: FFPE section of human stomach carcinoma (left) and mouse renal cell carcinoma (right). Antibody: Affinity purified rabbit anti-CCAR1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

CCAR1 Antibody - NB500-186 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CCAR1 Antibody [NB500-186] - Sample: FFPE section of human stomach carcinoma (left) and mouse renal cell carcinoma (right). Antibody: Affinity purified rabbit anti-CCAR1 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

CCAR1 Antibody - NBP1-86626 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CCAR1 Antibody [NBP1-86626] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

CCAR1 Antibody - NB100-258 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CCAR1 Antibody [NB100-258] - Detection of Human DIS on HeLa whole cell lystate using NB100-258. Controls: Normal IgG or another rabbit anti-DIS.

CCAR1 Antibody - NBP1-46158 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: CCAR1 Antibody [NBP1-46158] - NBP1-46158 (1ug/ml) staining of Rat Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

CCAR1 Antibody - NB500-188 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CCAR1 Antibody [NB500-188] - on HeLa whole cell lysate using NB500-188. CCAR1 was also immunoprecipitated with another rabbit anti-CCAR1 antibody, NB500-187, and NB500-188. Immunoprecipitated CCAR1 was blotted using NB500-188.

CCAR1 Polyclonal Antibody - bs-7064R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CCAR1 antibody produced in rabbit - HPA007856 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CCAR1: <B>Cat. No. HPA007856</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tissue showing nuclear staining of hepatocytes.

Anti-CCAR1 antibody produced in goat - SAB2501567 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CCAR1 <B>Cat. No. SAB2501567</B>: (1 μg/mL) staining of Rat Skeletal Muscle lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

CCAR1-Antibody - AF2225a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2225a (1 µg/ml) staining of Rat Skeletal Muscle lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

CCAR1 antibody - GTX110892 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-CCAR1 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX110892

CCAR1 Antibody (OAEB01259) - OAEB01259 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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