CCAR1

Gene Symbol	CCAR1
Entrez Gene	55749
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	cell division cycle and apoptosis regulator 1
Other Description	cell cycle and apoptosis regulatory protein 1|cell division cycle and apoptosis regulator protein 1|death inducer with SAP domain
Swissprots	A1L4P7 A8K9D4 Q9NVQ0 Q5VUP6 Q8IX12 Q9NWM6 Q5EBM3 Q9NVA7 Q6PIZ0 B4DNP8 A0JLT7 Q6X935 Q32NE3 B4DRK8 Q9H8N4
Accessions	CBX47496 EAW54300 EAW54301 EAW54302 Q8IX12 AF465616 AAO17319 AK000741 BAA91354 AK001701 BAA91847 AK023438 BAB14574 AK122871 AK292649 BAF85338 AK298004 BAG60310 AK299307 BAG61320 AK307550 AK307671 AK307704 AY249140 AAP82002 BC015475 AAH15475 BC026036 AAH26036 BC058846 BC089420 AAH89420 BC108682 AAI08683 BC130626 AAI30627 BC132725 AAI32726 BC144118 BM786237 BM905703 BU181074 BU617955 BX647943 CB136079 DA511293 DB636717 NM_001282959 NP_001269888 NM_001282960 NP_001269889 NM_018237 NP_060707 NR_104262
Function	Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation. {ECO:0000250, ECO:0000269|PubMed:12816952}.
Subcellular Location	Cytoplasm, perinuclear region {ECO:0000269|PubMed:12816952}.
Tissue Specificity	Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors. {ECO:0000269|PubMed:12816952}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DIS / CCAR1 Antibody Blocking Peptide - LS-E27242 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CCAR1 blocking peptide - GTX88234-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Pig, Rat, Bovine

DIS Peptide - AC21-2064-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CCAR1 Peptide - 42-273P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Mouse, Rat

CCAR1 fusion protein - ag18970 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CCAR1 fusion protein - ag18786 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Cell division cycle and apoptosis regulator protein 1(CCAR1) , - CSB-YP816898HU CSB-EP816898HU CSB-BP816898HU CSB-MP816898HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Cell division cycle and apoptosis regulator protein 1 (CCAR1), partial, Recombinant Protein - MBS1294417 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CCAR1, Peptide - MBS426406 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Rat, Dog, Bovine, Pig

CCAR1 Blocking Peptide Blocking Peptide (OESA11245) - OESA11245 from Aviva Systems Biology Category Peptide Prices $230.00 Sizes 50 µg Species Human

CCAR1 Recombinant Protein Antigen - NBP1-86626PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CCAR1 Peptide, Human - M34GP02448H from Creative Peptides Category Peptide Source Synthetic. Species Human

CCAR1 Recombinant Protein Antigen - NBP2-55611PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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