TMEM30A

Gene Symbol	TMEM30A
Entrez Gene	55754
Alt Symbol	C6orf67, CDC50A
Species	Human
Gene Type	protein-coding
Description	transmembrane protein 30A
Other Description	P4-ATPase flippase complex beta subunit TMEM30A|cell cycle control protein 50A
Swissprots	Q658Z3 E1P539 Q9NV96 Q9NSL9 A8K9V8 Q96H09
Accessions	EAW48743 EAW48744 EAW48745 Q9NV96 AA599967 AJ420517 AK001718 BAA91859 AK022883 AK292823 BAF85512 AK293225 BAG56764 AK295567 BAG58467 AL162046 CAB82389 AL832490 CAH56205 AL832815 CAH56262 BC009006 AAH09006 DA217148 DB239737 HQ447873 ADQ32357 NM_001143958 NP_001137430 NM_018247 NP_060717
Function	Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8
Subcellular Location	Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}. Apical cell membrane {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Transmembrane protein 30A full length protein - ab163206 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human TMEM30A Protein - H00055754-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TMEM30A Blocking Peptide - 33R-3094 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TMEM30A / CDC50A - H00055754-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TMEM30A / CDC50A - H00055754-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TMEM30A / CDC50A (transcript variant 1) - TP317257 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

TMEM30A Recombinant Protein Antigen - NBP1-86739PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TMEM30A Peptide, Human - M34GP16224H from Creative Peptides Category Peptide Source Synthetic. Species Human

Cell cycle control protein 50A (TMEM30A), Recombinant Protein - MBS7031813 from MyBioSource Category Protein Prices $1,170.00, $2,155.00, $3,360.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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