TMEM30A

Gene Symbol TMEM30A
Entrez Gene 55754
Alt Symbol C6orf67, CDC50A
Species Human
Gene Type protein-coding
Description transmembrane protein 30A
Other Description P4-ATPase flippase complex beta subunit TMEM30A|cell cycle control protein 50A
Swissprots Q658Z3 E1P539 Q9NV96 Q9NSL9 A8K9V8 Q96H09
Accessions EAW48743 EAW48744 EAW48745 Q9NV96 AA599967 AJ420517 AK001718 BAA91859 AK022883 AK292823 BAF85512 AK293225 BAG56764 AK295567 BAG58467 AL162046 CAB82389 AL832490 CAH56205 AL832815 CAH56262 BC009006 AAH09006 DA217148 DB239737 HQ447873 ADQ32357 NM_001143958 NP_001137430 NM_018247 NP_060717
Function Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8
Subcellular Location Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}. Apical cell membrane {ECO:0000250}.

Cdc50A CRISPR/Cas9 KO Plasmid (h) - sc-403231 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc50A HDR Plasmid (h) - sc-403231-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc50A Double Nickase Plasmid (h) - sc-403231-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc50A Double Nickase Plasmid (h2) - sc-403231-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc50A CRISPR Activation Plasmid (h) - sc-403231-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc50A CRISPR Activation Plasmid (h2) - sc-403231-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc50A Lentiviral Activation Particles (h) - sc-403231-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc50A Lentiviral Activation Particles (h2) - sc-403231-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc50A siRNA (h) - sc-95079 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cdc50A shRNA Plasmid (h) - sc-95079-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cdc50A shRNA (h) Lentiviral Particles - sc-95079-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU085941 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21615 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21615 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TMEM30A siRNA (Human) - CRJ0892 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TMEM30A - MBS8236768 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TMEM30A (NM_018247.3) - SHH430384 from Creative biogene

Category siRNA
Species Reactivities Human

TMEM30A shRNA Plasmid (Human) - CHJ0892 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TMEM30A miRNA 3'UTR clone - MiUTR4H-TG09054 from Creative biogene

Species Reactivities Human
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