SFRP2
| Gene Symbol | SFRP2 |
|---|---|
| Entrez Gene | 6423 |
| Alt Symbol | FRP-2, SARP1, SDF-5 |
| Species | Human |
| Gene Type | protein-coding |
| Description | secreted frizzled-related protein 2 |
| Other Description | SARP-1|sFRP-2|secreted apoptosis related protein 1|secreted apoptosis-related protein 1 |
| Swissprots | Q9HAP5 Q96HF1 O14778 B3KQR2 |
| Accessions | CAZ76869 EAX04949 Q96HF1 AA449032 AF017986 AAB70792 AF311912 AAG24923 AK075372 BAG52124 AK093922 BAG52787 AY359001 AAQ89360 BC008666 AAH08666 BM906663 BM924815 BQ130455 CN431016 NM_003013 NP_003004 |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. |
| Subcellular Location | Secreted {ECO:0000250}. |
| Tissue Specificity | Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. {ECO:0000269|PubMed:9391078, ECO:0000269|PubMed:9642118}. |
| Top Pathways | Wnt signaling pathway |
SFRP2 293 Cell Lysate - 400986 from ABBIOTEC
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sFRP-2 Overexpression Lysate (Native) - NBL1-15884 from Novus Biologicals
![Western Blot: SFRP2 Overexpression Lysate (Adult Normal) [NBL1-15884] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SFRP2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7912_SFRP2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15884-img0002.jpg)
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SFRP2 Over-expression Lysate Product - GWB-22D40C from Genway Biotech
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