SFRP2

Gene Symbol SFRP2
Entrez Gene 6423
Alt Symbol FRP-2, SARP1, SDF-5
Species Human
Gene Type protein-coding
Description secreted frizzled-related protein 2
Other Description SARP-1|sFRP-2|secreted apoptosis related protein 1|secreted apoptosis-related protein 1
Swissprots Q9HAP5 Q96HF1 O14778 B3KQR2
Accessions CAZ76869 EAX04949 Q96HF1 AA449032 AF017986 AAB70792 AF311912 AAG24923 AK075372 BAG52124 AK093922 BAG52787 AY359001 AAQ89360 BC008666 AAH08666 BM906663 BM924815 BQ130455 CN431016 NM_003013 NP_003004
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. {ECO:0000269|PubMed:9391078, ECO:0000269|PubMed:9642118}.
Top Pathways Wnt signaling pathway

FRP-2 (C-4) - sc-365524 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FRP-2 (C-4): sc-365524. Western blot analysis of FRP-2 expression in non-transfected (A) and human FRP-2 transfected (B) CMV whole cell lysates.

FRP-2 (D-20) - sc-31574 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FRP-2 (D-20): sc-31574. Western blot analysis of FRP-2 expression in COLO 320DM whole cell lysate.

FRP-2 (H-140) - sc-13940 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FRP-2 (H-140): sc-13940. Western blot analysis of FRP-2 expression in COLO 320DM (A) and MCF7 (B) whole cell lysates and mouse eye tissue extract (C).

FRP-2 (C-18) - sc-7426 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FRP-2 (C-18): sc-7426. Western blot analysis of FRP-2 expression in U-87 MG whole cell lysate.

Anti-SFRP2 antibody - ab92667 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab92667 stained SKNSH cells. The cells were 4% fomaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab92667, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-SFRP2 Antibody (aa25-50) - LS-C191289 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SFRP2 Antibody (aa25-50) - LS-C191290 from LifeSpan Bioscience

Prices $740.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-SFRP2 Antibody - LS-C341777 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SFRP2 Antibody (aa143-192) - LS-C102708 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SFRP2 antibody LS-C102708 Western blot of Jurkat lysate.

Anti-SFRP2 Antibody (aa119-168) - LS-C120353 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HeLa/COLO/HUVEC cells, using SFRP2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-SFRP2 Antibody (aa274-285) - LS-C61791 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.1 ug/ml) staining of Human Duodenum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SFRP2 Antibody - LS-C346077 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using SFRP2 antibody. Blue: DAPI for nuclear staining.

Anti-SFRP2 Antibody (aa25-295, clone 6C2) - LS-C340294 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6C2
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-SFRP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

sFRP-2 Antibody (755644) - MAB6838 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 755644
Western Blot sFRP-2 Antibody (755644)

sFRP-2 Antibody - NBP1-56609 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SFRP2 Antibody [NBP1-56609] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

sFRP-2 Antibody - NBP1-83423 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: sFRP-2 Antibody [NBP1-83423] - Staining of human epididymis shows strong membranous and cytoplasmic positivity in glandular cells.

sFRP-2 Antibody (EPR4832) - NBP1-95105 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4832
Western Blot: SFRP2 Antibody (EPR4832) [NBP1-95105] (A) U87-MG and (B) HUVEC cell lysates.

sFRP-2 Antibody - NB110-74715 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Goat
Clonality Polyclonal
Western Blot: sFRP-2 Antibody [NB110-74715] - Analysis of sFRP-2 in Human Duodenum lysate (35ug protein in RIPA buffer) using this antibody at 0.1 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

SARP1 Polyclonal Antibody - bs-9478R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
HeLa cell lysates probed with Rabbit Anti-SARP1 Polyclonal Antibody, Unconjugated (bs-9478R) at 1:300 overnight at 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:500 for 90 min at 37˚C.

Anti-SFRP2 antibody produced in rabbit - HPA002652 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SFRP2: <B>Cat. No. HPA002652</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human epididymis tissue showing cytoplasmic and/or membranous staining of glandular cells.

Anti-SFRP2 antibody produced in rabbit - SAB2103129 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SFRP2, antibody produced in rabbit: <B>Cat. No. SAB2103129</B>: Immunoblotting analysis of SFRP2 in Jurkat cell lysate with SFRP2 anitbody at 1 μg/mL.

Anti-SFRP2 antibody produced in rabbit - SAB4502745 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SFRP2, C-Terminal: <B>Cat. No. SAB4502745</B>: Immunoblotting analysis of extracts from HeLa/COLO/HuvEc cells, using Anti-SFRP2, C-Terminal antibody. The lane on the left was treated with the Anti-SFRP2, C-Terminal antibody. The lane on the right (negative control) was treated with both Anti-SFRP2, C-Terminal antibody and the synthesized immunogen peptide.

Anti-SFRP2 antibody produced in goat - SAB2500934 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SFRP2: <B>Cat. No. SAB2500934</B>: (0.1 μg/mL) staining of Human Duodenum lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

SFRP2 antibody - middle region (ARP56543_P050) - ARP56543_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SFRP2-Antibody - AF1984a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1984a (0.1 µg/ml) staining of Human Duodenum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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