PRKX

Gene Symbol PRKX
Entrez Gene 5613
Alt Symbol PKX1
Species Human
Gene Type protein-coding
Description protein kinase, X-linked
Other Description cAMP-dependent protein kinase catalytic subunit PRKX|protein kinase PKX1|protein kinase X|protein kinase X-linked|serine/threonine-protein kinase PRKX
Swissprots P51817
Accessions CBX55118 EAW98726 EAW98727 EAW98728 P51817 BC041073 AAH41073 BE675757 DN996851 DN997580 EU832357 ACE87614 EU832442 ACE86927 X85545 CAA59733 XM_005274560 XP_005274617 XM_005274561 XP_005274618 XM_011545544 XP_011543846 NM_005044 NP_005035
Function Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation. {ECO:0000269|PubMed:12082174, ECO:0000269|PubMed:16236808, ECO:0000269|PubMed:16491121, ECO:0000269|PubMed:17980165, ECO:0000269|PubMed:19367327, ECO:0000269|PubMed:21684272, ECO:0000269|PubMed:9860982}.
Subcellular Location Cytoplasm. Nucleus. Note=cAMP induces nuclear translocation.
Tissue Specificity Widely expressed (at protein level). Specifically expressed in blood by macrophages and granulocytes according to PubMed:9860982. {ECO:0000269|PubMed:15879576, ECO:0000269|PubMed:16236808, ECO:0000269|PubMed:7633447, ECO:0000269|PubMed:9860982}.
Top Pathways Adrenergic signaling in cardiomyocytes, Ovarian steroidogenesis, Wnt signaling pathway, Proteoglycans in cancer, Estrogen signaling pathway

Rat PRKX ELISA Kit (Sandwich ELISA) - LS-F9845 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 0.6 ng/ml
Range 1.56-100 ng/ml

PRKX (Human) IP-WB Antibody Pair - H00005613-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

PRKX (Human) IP-WB Antibody Pair - H00005613-PW2 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

protein kinase, X-linked, ELISA Kit - MBS9330324 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Kinase, X-Linked (PRKX), ELISA Kit - MBS2020234 from MyBioSource

Category ELISA Kit
Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.60ng/mL.
Range 1.56-100ng/mL

ELISA Kit for Protein Kinase, X-Linked (PRKX) - SEH312Ra from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.60ng/mL.
Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

Human PRKX ELISA Kit - E031663 from Biobool

Category ELISA Kit
Search more