JADE1

Gene Symbol JADE1
Entrez Gene 79960
Alt Symbol PHF17
Species Human
Gene Type protein-coding
Description jade family PHD finger 1
Other Description PHD finger protein 17|PHD protein Jade-1|gene for apoptosis and differentiation in epithelia|jade family PHD finger protein 1|protein Jade-1
Swissprots Q8NC41 D3DNY1 Q96SQ1 Q96JL8 Q4W5D5 Q9H692 Q6IE81 D3DNY0 Q6ZSL7
Accessions AAY40997 EAX05170 EAX05171 EAX05172 EAX05173 EAX05174 EAX05175 EAX05176 Q6IE81 AB058710 BAB47436 AF520952 AAM95612 AK026132 BAB15371 AK027620 BAB55239 AK074986 BAC11335 AK127326 BAC86931 AK304235 BAG65104 AK304815 BAG65565 BC032376 AAH32376 BI463062 BN000287 CAE30500 BX107708 DA478923 DA714593 DB085413 DB293142 DB451567 DC308420 DC308588 DQ891572 ABM82498 DQ894766 ABM85692 XM_005263232 XP_005263289 XM_011532260 XP_011530562 NM_001287437 NP_001274366 NM_001287439 NP_001274368 NM_001287440 NP_001274369 NM_001287441 NP_001274370 NM_001287442 NP_001274371 NM_001287443 NP_001274372 NM_024900 NP_079176 NM_199320 NP_955352
Function Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. {ECO:0000269|PubMed:15502158, ECO:0000269|PubMed:16046545, ECO:0000269|PubMed:16387653}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level). Down-regulated in renal cancer cells. {ECO:0000269|PubMed:12169691, ECO:0000269|PubMed:16046545}.

Jade-1 (E-14) - sc-160450 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Jade-1 (S-15) - sc-160452 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PHF17 antibody - ab66968 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Immunofluorescence of ab66968 on HeLa cells. (purified antibody concentration of 10ug/ml)

Anti-PHF17 antibody - ab116018 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PHF17 antibody (ab116018) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

Anti-JADE1 / PHF17 Antibody (aa20-51, AP) - LS-C266170 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-JADE1 / PHF17 Antibody (aa20-51, APC) - LS-C266171 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-JADE1 / PHF17 Antibody (aa20-51, Biotin) - LS-C266172 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-JADE1 / PHF17 Antibody (aa20-51, FITC) - LS-C266173 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-JADE1 / PHF17 Antibody (aa20-51, PE) - LS-C266175 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-JADE1 / PHF17 Antibody (aa20-51, Azide-free, HRP) - LS-C266174 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-JADE1 / PHF17 Antibody (aa20-51) - LS-C329964 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-JADE1 / PHF17 Antibody (C-Terminus) - LS-C80104 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-JADE1 / PHF17 Antibody (aa431-480) - LS-C110419 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PHF17 antibody LS-C110419 Western blot of Fetal Small Intestine lysate.

Anti-JADE1 / PHF17 Antibody (aa398-447) - LS-C80107 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-JADE1 / PHF17 Antibody (N-Terminus) - LS-C107884 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PHF17 antibody LS-C107884 Western blot of THP-1 cell lysate.

Anti-JADE1 / PHF17 Antibody - LS-C334650 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using JADE1 antibody.

Anti-JADE1 / PHF17 Antibody (aa650-700) - LS-C289525 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse Jade-1 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug), and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Jade-1 antibody used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. Jade-1 was also immunoprecipitated by rabbit anti-Jade-1 antibody BL10256, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B).

Anti-JADE1 / PHF17 Antibody (aa22-51) - LS-C163566 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PHF17 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Jade-1/PHF17 Antibody (658005) - MAB6275 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 658005
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line and Ramos human Burkitt's lymphoma cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Jade‑1/PHF17 Monoclonal Antibody (Catalog # MAB6275) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Jade‑1/PHF17 at approximately 92 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Jade-1/PHF17 Antibody - NBP1-83085 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Jade-1/PHF17 Antibody [NBP1-83085] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

Jade-1/PHF17 Antibody - NBP2-19798 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Jade-1/PHF17 Antibody - NBP2-19797 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PHF17 Antibody [NBP2-19797] - Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 7. 5% SDS PAGE gel, diluted at 1:500.

Jade-1/PHF17 Antibody - H00079960-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Jade-1/PHF17 Antibody [H00079960-B01P] - Analysis of PHF17 expression in transfected 293T cell line by PHF17 polyclonal antibody. Lane 1: PHF17 transfected lysate(55.99 KDa). Lane 2: Non-transfected lysate.

Jade-1/PHF17 Antibody - NBP1-47280 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: Jade-1/PHF17 Antibody [NBP1-47280] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug), and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Jade-1 antibody used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. Jade-1 was also immunoprecipitated by rabbit anti-Jade-1 antibody BL10256, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B).

Anti-PHF17 (AB1) antibody produced in rabbit - AV34715 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: fetal heart (<B>Cat. No. AV34715</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type fetal heart
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