JADE1

Gene Symbol JADE1
Entrez Gene 79960
Alt Symbol PHF17
Species Human
Gene Type protein-coding
Description jade family PHD finger 1
Other Description PHD finger protein 17|PHD protein Jade-1|gene for apoptosis and differentiation in epithelia|jade family PHD finger protein 1|protein Jade-1
Swissprots Q8NC41 D3DNY1 Q96SQ1 Q96JL8 Q4W5D5 Q9H692 Q6IE81 D3DNY0 Q6ZSL7
Accessions AAY40997 EAX05170 EAX05171 EAX05172 EAX05173 EAX05174 EAX05175 EAX05176 Q6IE81 AB058710 BAB47436 AF520952 AAM95612 AK026132 BAB15371 AK027620 BAB55239 AK074986 BAC11335 AK127326 BAC86931 AK304235 BAG65104 AK304815 BAG65565 BC032376 AAH32376 BI463062 BN000287 CAE30500 BX107708 DA478923 DA714593 DB085413 DB293142 DB451567 DC308420 DC308588 DQ891572 ABM82498 DQ894766 ABM85692 XM_005263232 XP_005263289 XM_011532260 XP_011530562 NM_001287437 NP_001274366 NM_001287439 NP_001274368 NM_001287440 NP_001274369 NM_001287441 NP_001274370 NM_001287442 NP_001274371 NM_001287443 NP_001274372 NM_024900 NP_079176 NM_199320 NP_955352
Function Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator, it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. {ECO:0000269|PubMed:15502158, ECO:0000269|PubMed:16046545, ECO:0000269|PubMed:16387653}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level). Down-regulated in renal cancer cells. {ECO:0000269|PubMed:12169691, ECO:0000269|PubMed:16046545}.

Human PHF17 full length protein - ab164168 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164168 on a 12.5% SDS-PAGE stained with Coomassie Blue.

JADE1 / PHF17 Antibody Blocking Peptide - LS-E2421 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

JADE1 / PHF17 Antibody Blocking Peptide - LS-E12351 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

JADE1 / PHF17 Antibody Blocking Peptide - LS-E12378 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

JADE1 / PHF17 Antibody Blocking Peptide - LS-E14356 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

JADE1 / PHF17 Antibody Blocking Peptide - LS-E14357 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Jade-1/PHF17 Protein - H00079960-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

PHF17-Antibody-N-term-Blocking-peptide - BP13432a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PHF17 / JADE1 - H00079960-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PHF17 / JADE1 - H00079960-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PHF17 fusion protein - ag4290 from Proteintech Group

Category Protein
Source E. coli-derived, T-HIS
Species Human

Recombinant Human Protein Jade-1(PHF17) ,partial - CSB-YP743563HU CSB-EP743563HU CSB-BP743563HU CSB-MP743563HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Jade-1/PHF17 Recombinant Protein Antigen - NBP1-83085PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PHF17 Peptide, Human - M34GP11692H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Protein Jade-1 (PHF17), partial, Recombinant Protein - MBS1376284 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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