ADGRE5

Gene Symbol ADGRE5
Entrez Gene 976
Alt Symbol CD97, TM7LN1
Species Human
Gene Type protein-coding
Description adhesion G protein-coupled receptor E5
Other Description CD97 antigen|CD97 molecule|leukocyte antigen CD97|seven transmembrane helix receptor|seven-span transmembrane protein|seven-transmembrane, heterodimeric receptor associated with inflammation
Swissprots Q8NG72 B2RBJ9 O00718 Q8TBQ7 O76101 P48960 A8K7Z4
Accessions BAC06178 CAA64333 CBX47491 CBX47492 CBX47493 CDM22289 EAW84412 EAW84413 P48960 AI890331 AK097264 BAG53442 AK225655 AK225677 AK292159 BAF84848 AK300343 BAG62088 AK304553 BAG65348 AK308368 AK314697 BAG37246 AU117846 AX775807 CAE11603 AX775809 CAE11604 AX775811 CAE11605 AX775813 CAE11606 AY545551 BC026690 AAH26690 BM545710 CB127827 DC381605 DC414739 U76764 AAB36682 X84700 CAA59173 XM_011528451 XP_011526753 NM_001025160 NP_001020331 NM_001784 NP_001775 NM_078481 NP_510966
Function Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompanied by detectable levels of soluble CD97 in the synovial fluid.

CD97 (G-8) - sc-166852 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD97 (G-8): sc-166852. Western blot analysis of CD97 expression in MIA PaCa-2 whole cell lysate.

CD97 (H-245) - sc-98576 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD97 (H-245): sc-98576. Western blot analysis of CD97 expression in SUP-T1 (A) and HeLa (B) whole cell lysates.

CD97 (K-18) - sc-26103 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD97 (C-20) - sc-26105 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD97 (C-20): sc-26105. Western blot analysis of CD97 expression in human PBL extract.

CD97 (E-17) - sc-31096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CD97 (G-19) - sc-31098 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CD97 antibody - ab116339 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CD97 antibody (ab116339) at 1/100 dilution + HL60 cell line lysate at 35 µg

Anti-CD97 antibody - ab125376 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CD97 antibody (ab125376) at 1 µg/ml + Human fetal lung lysate at 10 µg

Anti-CD97 antibody - ab72107 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD97 antibody (ab72107) at 2 µg/mlLane 1 : K562 cell lysateLane 2 : K562 cell lysate with immunizing peptide

Anti-CD97 antibody [EPR4427] - ab108368 from Abcam

Prices $388.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4427
ICC/IF image of ab108368 stained MDA-MB-231 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab108368 at 1/200 dilution overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-CD97 antibody [EPR4428] - ab134105 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4428
Immunohistochemical analysis of paraffin embedded Human colonic adenocarcinoma tissue labelling CD97 with ab134105 antibody at a dilution of 1/1000.

Anti-CD97 antibody [MEM-180] - ab2527 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-180
Overlay histogram showing U937 cells stained with ab2527 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab2527, 1µg/1x106 cells) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.

Anti-CD97 antibody [MEM-180] (FITC) - ab23490 from Abcam

Prices $186.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone MEM-180

Anti-CD97 antibody [MEM-180] (Phycoerythrin) - ab33229 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone MEM-180

Anti-CD97 antibody - C-terminal - ab155798 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD97 antibody - C-terminal (ab155798) at 1/1000 dilutionLane 1 : HepG2 whole cell lysateLane 2 : HCT116 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-CD97 antibody - N-terminal - ab140802 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human colon tissue labelling CD97 with ab140802 at 2 µg/ml.

Anti-ADGRE5 / CD97 Antibody - LS-C5747 from LifeSpan Bioscience

Prices $590.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-ADGRE5 / CD97 Antibody (PE) - LS-C5749 from LifeSpan Bioscience

Prices $455.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-ADGRE5 / CD97 Antibody (aa21-398) - LS-C35782 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ADGRE5 / CD97 Antibody (clone MEM-180) - LS-C45896 from LifeSpan Bioscience

Prices $260.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MEM-180

Anti-ADGRE5 / CD97 Antibody (RPE) - LS-C44041 from LifeSpan Bioscience

Prices $350.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-ADGRE5 / CD97 Antibody (clone MEM-180, FITC) - LS-C46372 from LifeSpan Bioscience

Prices $290.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone MEM-180

Anti-ADGRE5 / CD97 Antibody (aa1-512) - LS-C18770 from LifeSpan Bioscience

Prices $395.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal
Anti-CD97 Antibody - Western Blot. Western blot of Protein A purified anti-CD97 antibody shows detection of bands corresponding to free Fc-CD97- (5EGF) (lower arrowhead) and Fc-CD97- (5EGF) present as a complex (upper arrowhead) in lysates from COS cells. The left lane contains lysate from cells transfected with control DNA. The right lane contains lysate from COS cells expressing Fc-CD97- (5EGF). No staining was noted from bone marrow lysates taken from CD97 knockout mice. The identity of the band at ~65 kD appearing in all lanes is not known. The formation of the CD97 complex is currently under investigation. Approximately 10 ul of lysate was used in each lane. A 1:1000 dilution of the primary antibody was used. The image was processed using a 10-sec exposure. Personal Communication. Yvona Ward. NIH, NCI, CCR, Bethesda, MD.

Anti-ADGRE5 / CD97 Antibody - LS-C78800 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ADGRE5 / CD97 Antibody (APC) - LS-C78801 from LifeSpan Bioscience

Prices $485.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
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