CHD3

Gene Symbol CHD3
Entrez Gene 1107
Alt Symbol Mi-2a, Mi2-ALPHA, ZFH
Species Human
Gene Type protein-coding
Description chromodomain helicase DNA binding protein 3
Other Description ATP-dependent helicase CHD3|CHD-3|chromodomain-helicase-DNA-binding protein 3|hZFH|mi-2 autoantigen 240 kDa protein|zinc finger helicase|zinc-finger helicase (Snf2-like)
Swissprots Q12873 Q9Y4I0 D3DTQ9 E9PG89
Accessions EAW90114 EAW90115 EAW90116 Q12873 AF064844 AK096555 AK125928 BAG54266 AK296725 BAG59313 AK296937 BAG59488 AK308362 BC110648 AAI10649 BC156472 AAI56473 BM554923 BX283837 CB851648 U08379 AAC50228 U91543 AAC39923 XM_005256427 XP_005256484 XM_005256428 XP_005256485 XM_005256429 XP_005256486 XM_005256431 XP_005256488 XM_006721423 XP_006721486 XM_006721424 XP_006721487 XM_006721425 XP_006721488 XM_006721427 XP_006721490 XM_006721428 XP_006721491 XM_006721430 XP_006721493 XM_011523628 XP_011521930 XM_011523629 XP_011521931 XM_011523630 XP_011521932 NM_001005271 NP_001005271 NM_001005273 NP_001005273 NM_005852 NP_005843
Function Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. {ECO:0000269|PubMed:17626165, ECO:0000269|PubMed:9804427}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17626165}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17626165}. Note=Associates with centrosomes in interphase and mitosis.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:9688266}.

CHD3 Antibody - 4241 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa and Jurkat cells using CHD3 Antibody.

Mi2-α (C-16) - sc-12547 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Mi2-α (C-16): sc-12547. Western blot analysis of Mi2-α expression in HEK293 whole cell lysate.

Mi2-α (G-19) - sc-12545 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Mi2-α (G-19): sc-12545. Western blot analysis of Mi2- expression in HEK293 whole cell lysate.

Mi2-α (2172C1a) - sc-81323 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Mi2-α (2172C1a): sc-81323 Western Blot analysis of human recombinant Mi2-α fusion protein.

Anti-CHD3 antibody - ab66510 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHD3 antibody (ab66510) at 1 µg/mlLane 1 : Raji (Human Burkitt's lymphoma cell line) Whole Cell Lysate - tumor cell line (ab30124)Lane 2 : Y79 (Human retinoblastoma cell line) Whole Cell LysateLane 3 : TE 671 (Human Rhabdomyosarcoma) Whole Cell LysateLane 4 : Jurkat Whole Cell Lysate - Staurosporine Treated (24hr, 500nM)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-CHD3 antibody - ab176804 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHD3 antibody (ab176804) at 0.1 µg/mlLane 1 : HeLa cell lysate at 50 µgLane 2 : HeLa cell lysate at 15 µgLane 3 : 293T cell lysate at 50 µgLane 4 : Jurkat cell lysate at 50 µgdeveloped using the ECL technique

Anti-CHD3 antibody - ab114100 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ewing sarcoma (left) and mouse renal cell carcinoma (right) tissues labelling CHD3 with ab114100 at 1/1000 (1µg/ml). Detection: DAB.

Anti-CHD3 antibody - ab84528 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84528, at 1/250 dilution, staining CHD3 in formalin-fixed, paraffin-embedded human prostate carcinoma by Immunohistochemistry using DAB staining.

Anti-CHD3 antibody - ab54602 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
CHD3 antibody (ab54602) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human colon.

Anti-CHD3 antibody - ab135042 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-CHD3 antibody (ab135042) at 1/1000 dilution + Jurkat total cell extracts

Anti-CHD3 antibody [2172C1a] - ab51328 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2172C1a

Anti-CHD3 antibody [2G4] - ab101423 from Abcam

Prices $385.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2G4
All lanes : Anti-CHD3 antibody [2G4] (ab101423) at 1/500 dilutionLane 1 : Hela cell lysateLane 2 : K562 cell lysateLane 3 : Jurkat cell lysateLane 4 : NTERA-2 cell lysateLane 5 : HEK293 cell lysateLane 6 : Raji cell lysateLane 7 : Mouse brain lysate

Anti-CHD3 antibody [4B1-F1-G4] - ab151263 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B1-F1-G4
All lanes : Anti-CHD3 antibody [4B1-F1-G4] (ab151263) at 1/1000 dilutionLane 1 : Y79 cell lysateLane 2 : Raji cell lysate

Anti-CHD3 antibody [EPNCIR110A] - ab109195 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPNCIR110A
All lanes : Anti-CHD3 antibody [EPNCIR110A] (ab109195) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysateLane 3 : C6 cell lysateLane 4 : PC12 cell lysateLysates/proteins at 10 µg per lane.

Anti-CHD3 antibody [EPR7054] - ab133623 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7054
All lanes : Anti-CHD3 antibody [EPR7054] (ab133623) at 1/10000 dilutionLane 1 : K562 cell lysateLane 2 : Raji cell lysateLane 3 : HeLa cell lysateLane 4 : Jurkat cell lysateLane 5 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CHD3 Antibody (aa27-44) - LS-C3024 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHD3 Antibody (aa1641-1657) - LS-C3023 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHD3 Antibody - LS-C25612 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-CHD3 Antibody - LS-C79104 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-CHD3 Antibody (aa1575-1625) - LS-C79105 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-CHD3 Antibody (clone 2172C1a) - LS-C184401 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2172C1a

Anti-CHD3 Antibody (aa1551-1742, Biotin) - LS-C298214 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHD3 Antibody (aa1613-1820, Biotin) - LS-C298788 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHD3 Antibody (aa1551-1742, FITC) - LS-C302373 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHD3 Antibody (aa1613-1820, FITC) - LS-C302959 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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