Gene Symbol | SASS6 |
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Entrez Gene | 163786 |
Alt Symbol | SAS-6, SAS6 |
Species | Human |
Gene Type | protein-coding |
Description | spindle assembly 6 homolog (C. elegans) |
Other Description | hsSAS-6|spindle assembly abnormal protein 6 homolog |
Swissprots | D3DT55 Q8N3K0 Q6UVJ0 |
Accessions | EAW72974 EAW72975 Q6UVJ0 AK025750 AK302513 BAG63789 AK307824 AL834265 CAD38940 AY359522 AAQ57128 BC054889 BC101026 AAI01027 BX113339 BX641109 BX648406 DC400869 NM_001304829 NP_001291758 NM_194292 NP_919268 |
Function | Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers. {ECO:0000269|PubMed:15665853, ECO:0000269|PubMed:16244668, ECO:0000269|PubMed:17681131}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles (By similarity). Component of the centrosome. Associated only transiently with nascent procentrioles during centriole biogenesis. {ECO:0000250}. |
SAS-6 (91.390.21) - sc-81431 from Santa Cruz Biotechnology
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SAS-6 (G-1) - sc-376836 from Santa Cruz Biotechnology
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SAS-6 (C-20) - sc-82360 from Santa Cruz Biotechnology
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SAS-6 (G-20) - sc-82362 from Santa Cruz Biotechnology
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SAS-6 (H-300) - sc-98506 from Santa Cruz Biotechnology
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Anti-SASS6 antibody - ab85993 from Abcam
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Anti-SASS6 antibody - ab173763 from Abcam
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Anti-SASS6 antibody - ab67395 from Abcam
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Anti-SASS6 antibody - ab125511 from Abcam
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Anti-SAS6 / SASS6 Antibody (aa607-657) - LS-C126316 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa1-50) - LS-C126317 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa325-352, Biotin) - LS-C240397 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa325-352, APC) - LS-C240395 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa325-352, AP) - LS-C240394 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa325-352, FITC) - LS-C240398 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa325-352, PE) - LS-C240400 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa325-352, Azide-free, HRP) - LS-C248079 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa324-352) - LS-C324915 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa607-657) - LS-C288583 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa402-451) - LS-C146228 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa325-352) - LS-C158918 from LifeSpan Bioscience
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Anti-SAS6 / SASS6 Antibody (aa1-50) - LS-C288582 from LifeSpan Bioscience
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SASS6 Antibody - NBP2-20264 from Novus Biologicals
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SASS6 Antibody - NB100-93342 from Novus Biologicals
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SASS6 Antibody - NB100-93343 from Novus Biologicals
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