SASS6

Gene Symbol SASS6
Entrez Gene 163786
Alt Symbol SAS-6, SAS6
Species Human
Gene Type protein-coding
Description spindle assembly 6 homolog (C. elegans)
Other Description hsSAS-6|spindle assembly abnormal protein 6 homolog
Swissprots D3DT55 Q8N3K0 Q6UVJ0
Accessions EAW72974 EAW72975 Q6UVJ0 AK025750 AK302513 BAG63789 AK307824 AL834265 CAD38940 AY359522 AAQ57128 BC054889 BC101026 AAI01027 BX113339 BX641109 BX648406 DC400869 NM_001304829 NP_001291758 NM_194292 NP_919268
Function Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers. {ECO:0000269|PubMed:15665853, ECO:0000269|PubMed:16244668, ECO:0000269|PubMed:17681131}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles (By similarity). Component of the centrosome. Associated only transiently with nascent procentrioles during centriole biogenesis. {ECO:0000250}.

SAS-6 CRISPR/Cas9 KO Plasmid (h) - sc-401644 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAS-6 HDR Plasmid (h) - sc-401644-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAS-6 Double Nickase Plasmid (h) - sc-401644-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAS-6 Double Nickase Plasmid (h2) - sc-401644-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAS-6 CRISPR Activation Plasmid (h) - sc-401644-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAS-6 CRISPR Activation Plasmid (h2) - sc-401644-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAS-6 Lentiviral Activation Particles (h) - sc-401644-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAS-6 Lentiviral Activation Particles (h2) - sc-401644-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAS-6 siRNA (h) - sc-76454 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SAS-6 shRNA Plasmid (h) - sc-76454-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SAS-6 shRNA (h) Lentiviral Particles - sc-76454-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU014091 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18859 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18859 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10406 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10406

SASS6 siRNA (Human) - CRJ6001 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SASS6 - MBS8221972 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SASS6 (NM_194292.1) - SHH401984 from Creative biogene

Category siRNA
Species Reactivities Human

Human SASS6 siRNA - orb276502 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SASS6 shRNA Plasmid (Human) - CHJ6001 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SASS6 miRNA 3'UTR clone - MiUTR1H-09142 from Creative biogene

Species Reactivities Human
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