Gene Symbol | CD300A |
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Entrez Gene | 11314 |
Alt Symbol | CLM-8, CMRF-35-H9, CMRF-35H, CMRF35-H, CMRF35-H9, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC1/IRC2, IRC2, IRp60 |
Species | Human |
Gene Type | protein-coding |
Description | CD300a molecule |
Other Description | CD300 antigen-like family member A|CD300a antigen|CMRF35-like molecule 8|CMRF35H leukocyte immunoglobulin-like receptor|NK inhibitory receptor|immunoglobulin superfamily member 12|inhibitory receptor protein 60|leukocyte membrane antigen |
Swissprots | A8MW96 Q9HD97 Q9UMT0 Q9P0F3 Q9UBK4 Q9UMS9 Q9UGN4 O95100 |
Accessions | AAF89957 CCF77000 CDM22292 EAW89166 EAW89167 EAW89168 Q9UGN4 AF020314 AAD01646 AF161346 AAF28906 AJ010101 CAB52291 AJ010102 CAB52292 AJ010103 CAB52293 AJ224864 CAB55347 AJ238323 CAB66145 AK309631 AK309636 BC020681 BC032352 AAH32352 BF059016 BM923070 XM_005256990 XP_005257047 XM_005256991 XP_005257048 XM_005256992 XP_005257049 XM_006721656 XP_006721719 XM_011524254 XP_011522556 NM_001256841 NP_001243770 NM_007261 NP_009192 |
Function | Inhibitory receptor which may contribute to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. {ECO:0000269|PubMed:10746781, ECO:0000269|PubMed:16339535, ECO:0000269|PubMed:9701027}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. {ECO:0000269|PubMed:10540326, ECO:0000269|PubMed:16339535, ECO:0000269|PubMed:9701027}. |
Active human CD300 antigen protein fragment - ab185267 from Abcam
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Human CD300 antigen full length protein - ab161408 from Abcam
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Human CD300 antigen protein fragment - ab152065 from Abcam
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Human CD300 antigen protein fragment - ab185418 from Abcam
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Recombinant Human CD300a/LMIR1 Protein - H00011314-P01 from Novus Biologicals
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Recombinant Human CD300a/LMIR1 Protein - NBP2-22749 from Novus Biologicals
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CD300a/LMIR1 Recombinant Protein - H00011314-G01 from Novus Biologicals
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Recombinant Human CD300a/LMIR1 Fc Chimera, CF - 2640-LM-050 from R&D Systems
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Human CD300A protein - orb191327 from Biorbyt
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Human CD300A protein - orb138393 from Biorbyt
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Human CD300A His tag protein - orb84315 from Biorbyt
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Human LMIR1CD300A protein - orb180214 from Biorbyt
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CD300A protein (His tag) - 80R-2938 from Fitzgerald
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CD300A / CMRF35H (18-128, His-tag) - AR51056PU-N from Acris Antibodies
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CD300A / CMRF35H (18-128, His-tag) - AR51056PU-S from Acris Antibodies
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CD300A / CMRF35H - H00011314-G01 from Acris Antibodies
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CD300A / CMRF35H - H00011314-P01-10 from Acris Antibodies
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CD300A / CMRF35H - H00011314-P01-25 from Acris Antibodies
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CD300A, 18-128aa, Human, His tag, E.coli - 01-P2232 from ARP American Research Products
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CD300A, Human, Recombinant - 19-C574 from ARP American Research Products
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LMIR1 Recombinant Protein - 96-151 from ProSci
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CD300A fusion protein - ag5776 from Proteintech Group
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CD300A fusion protein - Ag4303 from Proteintech Group
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Recombinant Human CLM-8 Protein - BP001350-C574 from Syd Labs
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Recombinant Human CD300A, His tagged - CD300A-3976H from Creative Biomart
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