CACNA1I

Gene Symbol CACNA1I
Entrez Gene 8911
Alt Symbol Cav3.3, ca(v)3.3
Species Human
Gene Type protein-coding
Description calcium channel, voltage-dependent, T type, alpha 1I subunit
Other Description calcium channel, voltage-dependent, alpha 1I subunit|voltage-dependent T-type calcium channel subunit alpha-1I|voltage-gated calcium channel subunit alpha Cav3.3
Swissprots B0QY13 O95504 Q9UNE6 B0QY12 Q9UH30 B0QY14 Q9NZC8 Q5JZ88 Q9UH15 Q8NFX6 Q9P0X4 Q9ULU9 Q7Z6S9
Accessions EAW60345 EAW60346 EAW60347 EAW60348 EAW60349 EAW60350 EAW60351 Q9P0X4 AB032946 BAA86434 AF129133 AAD45251 AF142567 AAF25722 AF211189 AAF44626 AF393329 AAM67414 BC042972 N52765 XM_011530480 XP_011528782 XM_011530481 XP_011528783 NM_001003406 NP_001003406 NM_021096 NP_066919
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Isoform alpha-1I gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H (By s
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Brain specific.
Top Pathways MAPK signaling pathway, Calcium signaling pathway, Circadian entrainment

T-type Ca ++ CP α1I (C-15) - sc-16266 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

T-type Ca ++ CP α1I (H-160) - sc-28615 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
T-type Ca++ CP α1I (H-160): sc-28615. Western blot analysis of T-type Ca<sup>++</sup> CP α1I expression in HeLa whole cell lysate.

T-type Ca ++ CP α1I (N-20) - sc-16264 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CACNA1I antibody - ab81100 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-CACNA1I antibody - ab56439 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab56439 CACNA1I antibody at 1ug/ml.

Anti-CACNA1I / Cav3.3 Antibody - LS-C26750 from LifeSpan Bioscience

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CACNA1I / Cav3.3 Antibody (Cytoplasmic Domain) - LS-C94073 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-CACNA1I / Cav3.3 Antibody - LS-C140730 from LifeSpan Bioscience

Prices $460.00
Sizes 10 blot
Host Rabbit
Clonality Polyclonal

Anti-CACNA1I / Cav3.3 Antibody (aa233-332) - LS-C306690 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CACNA1I / Cav3.3 Antibody (aa755-804) IHC-plus™ - LS-B5617 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CACNA1I / Cav3.3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5617 concentration 5 ug/ml.

CACNA1I Antibody - NBP1-30674 from Novus Biologicals

Prices $299.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: CACNA1I Antibody [NBP1-30674] - Staining of a cytospin preparation of peripheral blood mononuclear cells (PBMC) isolated from buffycoat. Cells were left to air dry and then fixed with cold acetone (90 seconds) and blocked with PBS containing 1% FCS and 0.1% saponin (blocking buffer) for 20 minutes. Cells were then washed twice in PBS and incubated with Mouse monoclonal to human Cathelicidin (CAP-18, antibacterial protein LL-37, CAMP, CRAMP, FALL39): OSX12 clone at a concentration of 10 ug/ml. DAPI counterstained appearing in blue. The antibody selectively recognizes polymorphonuclar cells.

CACNA1I Antibody - NBP1-20109 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CACNA1I Antibody [NBP1-20109] - IHC on rat spinal cord (free floating sections) using Rabbit antibody to a cytoplasmic domain of CACNA1I (Cav3.3): whole serum at 1 : 300 dilution incubated overnight at 4C and developed with DAB/Ni.

CACNA1I Antibody (3H5) - H00008911-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3H5
Sandwich ELISA: CACNA1I Antibody (3H5) [H00008911-M02] - Detection limit for recombinant GST tagged CACNA1I is approximately 0.3ng/ml as a capture antibody.

Monoclonal Anti-CACNA1I antibody produced in mouse - SAB1404652 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F5
<B>Immunoblotting</B><BR/>Monoclonal Anti-CACNA1I: <B>Cat. No. SAB1404652</B>: Antibody concentration: 1 μg/mL. Specific band of ~37 kDa using immunogen protein lysate.

Anti-CACNA1I antibody produced in rabbit - SAB2104240 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CACNA1I, antibody produced in rabbit: <B>Cat. No. SAB2104240</B>: Immunoblotting analysis of CACNA1I in fetal Small intestine with CACNA1I anitbody at 1 μg/mL.

Anti-Calcium Channel CaV3.3 (α1I) antibody produced in rabbit - C4616 from Sigma-Aldrich

Prices $597.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Ca<SUB>v</SUB>3.3: <B>Cat. No. C4616</B>: Western blot analysis of Rat brain membranes. <BR/><B>Lanes</B><BR/>1. Anti-Ca<SUB>v</SUB>3.3 antibody, (1:200). <BR/>2. Anti-Ca<SUB>v</SUB>3.3 antibody, preincubated with the control peptide antigen.

Monoclonal Anti-CACNA1I antibody produced in mouse - WH0008911M2 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3H5
<B>Immunoblotting</B><BR/>Monoclonal Anti-CACNA1I, <B>Cat. No. WH0008911M2</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37 kDa using immunogen protein lysate.

CACNA1I antibody - middle region (ARP35319_P050) - ARP35319_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACNA1I-Antibody-monoclonal-M02 - AT1364a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3H5
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .

Cav3.3 antibody, Internal - GTX47661 from GeneTex

Prices $329.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-Cav3.3 antibody, Internal used in Western blot. GTX47661

CACNA1I antibody - 70R-5133 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

CACNA1I antibody - AP05135PU-N from Acris Antibodies

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CACNA1I antibody - H00008911-M01 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F5

CACNA1I antibody - H00008911-M02 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3H5
Detection limit for recombinant GST tagged CACNA1I is approximately 0.3ng/ml as a capture antibody.

CACNA1I-Specific antibody - 19534-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal
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