LCP1

Gene Symbol LCP1
Entrez Gene 3936
Alt Symbol CP64, HEL-S-37, L-PLASTIN, LC64P, LPL, PLS2
Species Human
Gene Type protein-coding
Description lymphocyte cytosolic protein 1 (L-plastin)
Other Description L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P)|LCP-1|Lymphocyte cytosolic protein-1 (plasmin)|bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin))|epididymis secretory protein Li 37|plastin 2|plastin-2
Swissprots P13796 Q5TBN4 B4DUA0 B2R613
Accessions EAX08757 EAX08758 P13796 AB208984 BAD92221 AK058152 AK093568 AK097174 AK097275 BAG53443 AK129625 AK223305 BAD97025 AK300556 BAG62262 AK309009 AK312393 BAG35310 AY960627 BC007673 AAH07673 BC010271 AAH10271 BC015001 BC053839 BF893502 CR936795 DA820090 DB156931 DQ892935 ABM83861 DQ896184 ABM87183 EU794648 ACJ13702 J02923 AAA63236 M22300 AAB02845 M34426 AAA36184 XM_005266374 XP_005266431 NM_002298 NP_002289
Function Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. {ECO:0000269|PubMed:16636079, ECO:0000269|PubMed:17294403}.
Subcellular Location Cytoplasm, cytoskeleton. Cell junction. Cell projection. Cell projection, ruffle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28. Associated with the actin cytoskeleton at membrane ruffles (By similarity). Relocalizes to actin-rich cell projections upon serine phosphorylation. {ECO:0000250}.
Tissue Specificity Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells. {ECO:0000269|PubMed:3261603}.

Phospho-LCP1 (Tyr28) Antibody - 5277 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from MOLT-15 and MV-4-11 cells, untreated or treated with λ-phosphatase, using Phospho-LCP1 (Tyr28) Antibody (upper) and LCP1 Antibody #5350 (lower).

LCP1 Antibody - 5350 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using LCP1 Antibody.

LCP1 (D1C3) Rabbit mAb - 3588 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1C3
Western blot analysis of extracts from various cell lines using LCP1 (D1C3) Rabbit mAb.

L-Plastin (B-9) - sc-133218 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
L-Plastin (B-9): sc-133218. Western blot analysis of L-Plastin expression in non-transfected 293T: sc-117752 (A), human L-Plastin transfected 293T: sc-113499 (B), CCRF-CEM (C), K-562 (D) and RAW 264.7 (E) whole cell lysates.

L-Plastin (C-4) - sc-133219 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
L-Plastin (C-4): sc-133219. Western blot analysis of L-Plastin expression in non-transfected 293T: sc-117752 (A), human L-Plastin transfected 293T: sc-113499 (B), CCRF-CEM (C), K-562 (D) and RAW 264.7 (E) whole cell lysates.

L-Plastin (E-17) - sc-30506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
L-Plastin (E-17): sc-30506. Western blot analysis of L-Plastin expression in rat PBL (A) and THP-1 (B) whole cell lysates.

L-Plastin (D-16) - sc-16657 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
L-plastin (D-16): sc-16657. Western blot analysis of L-plastin expression in CCRF-CEM (A) and RAW 264.7 (B) whole cell lysates.

Anti-Plastin L antibody - ab83496 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Plastin L antibody (ab83496) at 1/500 dilutionLane 1 : HL60 cell lysateLane 2 : Mouse spleen lysate

Anti-Plastin L antibody - ab154320 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of methanol fixed A431 cells, labeling Plastin L with ab154320 at 1/500 dilution. Blue: Hoechst 33343 staining.

Anti-Plastin L antibody - ab138755 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Plastin L antibody (ab138755) at 1/100 dilution + Jurkat cell lysate at 35 µg

Anti-Plastin L antibody [EPR4277] - ab109124 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4277
All lanes : Anti-Plastin L antibody [EPR4277] (ab109124) at 1/1000 dilutionLane 1 : THP1 cell lysatesLane 2 : K562 cell lysatesLane 3 : Jurkat cell lysatesLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-Rabbit at 1/2000 dilution

Anti-Plastin L antibody [EPR4278] - ab109129 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4278
All lanes : Anti-Plastin L antibody [EPR4278] (ab109129) at 1/10000 dilutionLane 1 : THP-1 cell lysateLane 2 : Jurkat cell lysateLane 3 : K562 cell lysateLysates/proteins at 10 µg per lane.

Anti-Plastin L antibody [LPL4A.1] - ab80729 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone LPL4A.1
Anti-Plastin L antibody [LPL4A.1] (ab80729) at 1 µg/ml + Human Cells-15 Lysate

Anti-Plastin L antibody [LPL4A.1] - ab3290 from Abcam

Host Mouse
Clonality Monoclonal
Clone LPL4A.1

Anti-LCP1 / L-Plastin Antibody (aa138-172) - LS-C344326 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from Zebrafish tissue lysate with (DANRE) lcp1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

Anti-LCP1 / L-Plastin Antibody (aa305-339) - LS-C344622 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from Zebrafish tissue lysate with (DANRE) lcp1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

Anti-LCP1 / L-Plastin Antibody (Internal, clone EPR4278) IHC-plus™ - LS-B11091 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4278
Anti-LCP1 / L-Plastin antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-LCP1 / L-Plastin Antibody (clone SPM414) - LS-C189160 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone SPM414

Anti-LCP1 / L-Plastin Antibody - LS-C131506 from LifeSpan Bioscience

Prices $355.00
Sizes 40 µl
Host Rabbit
Clonality Polyclonal

Anti-LCP1 / L-Plastin Antibody - LS-C131505 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LCP1 / L-Plastin Antibody (Internal) - LS-C210139 from LifeSpan Bioscience

Prices $295.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-LCP1 / L-Plastin Antibody (aa506-555) - LS-C81905 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Placenta lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-LCP1 / L-Plastin Antibody (aa74-123) - LS-C81904 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-LCP1 / L-Plastin Antibody (aa305-335, Biotin) - LS-C261791 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LCP1 / L-Plastin Antibody (aa305-335, APC) - LS-C261790 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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