LCP1

Gene Symbol	LCP1
Entrez Gene	3936
Alt Symbol	CP64, HEL-S-37, L-PLASTIN, LC64P, LPL, PLS2
Species	Human
Gene Type	protein-coding
Description	lymphocyte cytosolic protein 1 (L-plastin)
Other Description	L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P)|LCP-1|Lymphocyte cytosolic protein-1 (plasmin)|bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin))|epididymis secretory protein Li 37|plastin 2|plastin-2
Swissprots	P13796 Q5TBN4 B4DUA0 B2R613
Accessions	EAX08757 EAX08758 P13796 AB208984 BAD92221 AK058152 AK093568 AK097174 AK097275 BAG53443 AK129625 AK223305 BAD97025 AK300556 BAG62262 AK309009 AK312393 BAG35310 AY960627 BC007673 AAH07673 BC010271 AAH10271 BC015001 BC053839 BF893502 CR936795 DA820090 DB156931 DQ892935 ABM83861 DQ896184 ABM87183 EU794648 ACJ13702 J02923 AAA63236 M22300 AAB02845 M34426 AAA36184 XM_005266374 XP_005266431 NM_002298 NP_002289
Function	Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. {ECO:0000269|PubMed:16636079, ECO:0000269|PubMed:17294403}.
Subcellular Location	Cytoplasm, cytoskeleton. Cell junction. Cell projection. Cell projection, ruffle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28. Associated with the actin cytoskeleton at membrane ruffles (By similarity). Relocalizes to actin-rich cell projections upon serine phosphorylation. {ECO:0000250}.
Tissue Specificity	Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells. {ECO:0000269|PubMed:3261603}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LCP1-Antibody-Center-Blocking-Peptide - BP18836c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human LCP1 protein - orb246756 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human LCP1 protein - orb244337 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

LCP1 fusion protein - ag3571 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

LCP1 fusion protein - ag19253 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Lymphocyte Cytosolic Protein 1 (LCP1) - RPC561Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Lymphocyte Cytosolic Protein 1 (LCP1) - RPC561Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Plastin-2(LCP1) - CSB-YP012824HU CSB-BP012824HU CSB-MP012824HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Plastin-2(LCP1) - CSB-EP012824HU from Cusabio Category Protein Source Yeast Species Human

Plastin 2 / LCP1 - TP301670 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Plastin-2 , Recombinant Protein - MBS953535 from MyBioSource Category Protein Prices $110.00, $190.00, $285.00, $460.00, $750.00, $1,180.00, $1,450.00, $1,805.00, $2,100.00, $2,600.00, $2,855.00, $3,560.00 Sizes 10 µg (Yeast), 50 µg (Yeast), 100 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli), 50 µg (Baculovirus), 100 µg (Baculovirus), 50 µg (Mammalian-Cell), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell

LCP1/plastin-2, Peptide - MBS428115 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

LCP1 Recombinant Protein (OPCA01692) - OPCA01692 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

LCP1 Recombinant Protein (OPCA02707) - OPCA02707 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

LCP1 Recombinant Protein (OPCD04876) - OPCD04876 from Aviva Systems Biology Category Protein Source E.coli Species Human

Recombinant human Plastin-2 - AP70492 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Recombinant Homo sapiens Plastin-2 - AP72645 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast

Lymphocyte Cytosolic Protein 1, Recombinant Protein - MBS2029108 from MyBioSource Category Protein Prices $185.00, $385.00, $595.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Plastin-2, Recombinant Protein - MBS9422370 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Human

Plastin-2, Recombinant Protein - MBS9420408 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Recombinant Human Plastin-2 (LCP1) - RPC20639 from Biomatik Category Protein Prices $371.00, $1,866.00 Sizes 100 µg, 1 mg Source Baculovirus Species Human

Recombinant Human Plastin-2 (LCP1) - RPC21587 from Biomatik Category Protein Prices $187.00, $342.00, $1,692.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Human

Recombinant Human Plastin-2 (LCP1) - RPC24785 from Biomatik Category Protein Prices $224.00, $410.00, $2,030.00 Sizes 50 µg, 100 µg, 1 mg Source Yeast Species Human

Human LCP1 protein - orb419291 from Biorbyt Category Protein Species Human

Recombinant Human LCP1 Protein (2-627 aa), His-tagged - LCP1-1439H from Creative Biomart Category Protein Source Yeast Species Human

Search more