Gene Symbol | SEPT6 |
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Entrez Gene | 23157 |
Alt Symbol | SEP2, SEPT2 |
Species | Human |
Gene Type | protein-coding |
Description | septin 6 |
Other Description | septin 2|septin-6 |
Swissprots | Q96P87 Q14141 Q96GR1 Q96P86 Q96A13 Q5JTK0 Q969W5 |
Accessions | EAW89851 EAW89852 EAW89853 EAW89854 EAW89855 EAW89856 EAW89857 EAW89858 Q14141 AF397023 AAN76547 AF403058 AAK98547 AF403059 AAK98548 AF403060 AAK98549 AF403061 AAK98550 AF403062 AAK98551 AK026589 AK290977 BAF83666 AK298487 BAG60696 AK299273 BAG61293 AK303116 BAG64222 AK303224 BAG64311 AL833677 AY005981 AAF97496 AY034177 AAK61492 AY679521 AAT80339 BC009291 AAH09291 BC011922 AAH11922 BC036240 AAH36240 BC069231 AAH69231 D50918 BAA09477 DC336432 HQ447923 ADQ32407 XM_005262400 XP_005262457 XM_006724748 XP_006724811 XM_006724750 XP_006724813 XM_011531317 XP_011529619 XM_011531318 XP_011529620 XR_938548 NM_015129 NP_055944 NM_145799 NP_665798 NM_145800 NP_665799 NM_145802 NP_665801 |
Function | Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. {ECO:0000269|PubMed:17229681, ECO:0000269|PubMed:17803907}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15774761}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:15774761}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:15774761}. Cleavage furrow {ECO:0000269|PubMed:15774761}. Midbody {ECO:0000269|PubMed:15774761}. Note=In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:15915442}. |
Top Pathways | Bacterial invasion of epithelial cells |
Human SEPT6 full length protein - ab113123 from Abcam
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SEPT6 / Septin 6 Antibody Blocking Peptide - LS-E6082 from LifeSpan Bioscience
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SEPT6 / Septin 6 Antibody Blocking Peptide - LS-E16856 from LifeSpan Bioscience
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SEPT6 / Septin 6 Antibody Blocking Peptide - LS-E16857 from LifeSpan Bioscience
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SEPT6 / Septin 6 Antibody Blocking Peptide - LS-E26878 from LifeSpan Bioscience
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Septin-6 Recombinant Protein - H00023157-P02 from Novus Biologicals
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Septin-6 Recombinant Protein - H00023157-P01 from Novus Biologicals
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Recombinant Human Septin-6 Protein - NBP1-72485 from Novus Biologicals
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SEPT6-Antibody-C-term-Blocking-Peptide - BP18676b from Abgent, a WuXi AppTec company
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SEPT6 blocking peptide - GTX88399-PEP from GeneTex
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Human SEPT6 protein - orb169274 from Biorbyt
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SEPT6 Immunizing peptide - orb16869 from Biorbyt
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38961 protein (His tag) - 80R-1998 from Fitzgerald
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Septin 6 Blocking Peptide - abx063761 from Abbexa
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SEPT6 Peptide - AC21-1713-P from Abcore
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SEPT6 - H00023157-P01-02 from Acris Antibodies
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Septin-6 / SEPT6 (1-434, His-tag) - AR50069PU-N from Acris Antibodies
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Septin-6 / SEPT6 (1-434, His-tag) - AR50069PU-S from Acris Antibodies
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Septin-6 / SEPT6 - H00023157-P02 from Acris Antibodies
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Septin-6 / SEPT6 - H00023157-P02-10 from Acris Antibodies
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Septin-6 / SEPT6 - H00023157-P02-25 from Acris Antibodies
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Septin-6, Human Recombinant - 228-13388-1 from RayBiotech
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Recombinant Human Septin-6 - 228-13388-2 from RayBiotech
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Recombinant Human Septin-6 - 228-13388-3 from RayBiotech
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SEPT6, 1-434aa, Human, His tag, E.coli - 01-1764-6 from ARP American Research Products
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