SEPT6

Gene Symbol SEPT6
Entrez Gene 23157
Alt Symbol SEP2, SEPT2
Species Human
Gene Type protein-coding
Description septin 6
Other Description septin 2|septin-6
Swissprots Q96P87 Q14141 Q96GR1 Q96P86 Q96A13 Q5JTK0 Q969W5
Accessions EAW89851 EAW89852 EAW89853 EAW89854 EAW89855 EAW89856 EAW89857 EAW89858 Q14141 AF397023 AAN76547 AF403058 AAK98547 AF403059 AAK98548 AF403060 AAK98549 AF403061 AAK98550 AF403062 AAK98551 AK026589 AK290977 BAF83666 AK298487 BAG60696 AK299273 BAG61293 AK303116 BAG64222 AK303224 BAG64311 AL833677 AY005981 AAF97496 AY034177 AAK61492 AY679521 AAT80339 BC009291 AAH09291 BC011922 AAH11922 BC036240 AAH36240 BC069231 AAH69231 D50918 BAA09477 DC336432 HQ447923 ADQ32407 XM_005262400 XP_005262457 XM_006724748 XP_006724811 XM_006724750 XP_006724813 XM_011531317 XP_011529619 XM_011531318 XP_011529620 XR_938548 NM_015129 NP_055944 NM_145799 NP_665798 NM_145800 NP_665799 NM_145802 NP_665801
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. {ECO:0000269|PubMed:17229681, ECO:0000269|PubMed:17803907}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15774761}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:15774761}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:15774761}. Cleavage furrow {ECO:0000269|PubMed:15774761}. Midbody {ECO:0000269|PubMed:15774761}. Note=In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:15915442}.
Top Pathways Bacterial invasion of epithelial cells

Septin (E-4) - sc-271670 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Septin (E-4): sc-271670. Western blot analysis of Septin 11 expression in non-transfected: sc-117752 (A) and human Septin 11 transfected: sc-116662 (B) 293T whole cell lysates.

Septin 6 (E-18) - sc-324301 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Septin 6 (T-15) - sc-324300 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Septin 6 (H-60) - sc-20180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Septin 6 (H-60): sc-20180. Western blot analysis of Septin 6 expression in K-562 (A) CCRF-CEM (B) and MOLT-4 (C) whole cell lysates.

Anti-SEPT6 antibody - ab106944 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab106944 (3.8µg/ml) staining of paraffin embedded Human Tonsil following Steamed antigen retrieval with citrate buffer pH 6 and AP-staining shows specific staining in dividing cells just outside a germinal centre.

Anti-SEPT6 antibody - ab88340 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-SEPT6 antibody (ab88340) at 1 µg/ml + recombinant protein (immunogen) at 0.2 µg

Anti-SEPT6 antibody - ab138036 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SEPT6 antibody (ab138036) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-SEPT6 antibody - C-terminal - ab138644 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SEPT6 antibody - C-terminal (ab138644) at 1/100 dilution + NIH 3T3 cell lysate at 35 µg

Anti-SEPT6 / Septin 6 Antibody (aa301-350) - LS-C80859 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.

Anti-SEPT6 / Septin 6 Antibody (aa208-257) - LS-C200652 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HeLa cells using SEPT6 antibody.

Anti-SEPT6 / Septin 6 Antibody (aa399-426, APC) - LS-C269006 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT6 / Septin 6 Antibody (aa51-100) - LS-C80860 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 15%.

Anti-SEPT6 / Septin 6 Antibody (aa399-426, AP) - LS-C269007 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT6 / Septin 6 Antibody (aa399-426, Biotin) - LS-C269008 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT6 / Septin 6 Antibody (aa399-426, FITC) - LS-C269009 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT6 / Septin 6 Antibody (aa399-426, Azide-free, HRP) - LS-C269010 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT6 / Septin 6 Antibody (aa399-426, PE) - LS-C269013 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT6 / Septin 6 Antibody (aa267-312) - LS-C313949 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SEPT6 / Septin 6 Antibody (aa399-426) - LS-C325007 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPT6 / Septin 6 Antibody (aa400-426) - LS-C158942 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SEPT6 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The SEPT6 antibody detected the SEPT6 protein (arrow).

Anti-SEPT6 / Septin 6 Antibody (clone 1D6) IHC-plus™ - LS-B6216 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1D6
Anti-SEPT6 / Septin 6 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6216 concentration 3 ug/ml.

Anti-SEPT6 / Septin 6 Antibody (aa523-534) IHC-plus™ - LS-B9200 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-SEPT6 / Septin 6 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Septin-6 Antibody - NBP1-89626 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Septin-6 Antibody [NBP1-89626] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Septin-6 Antibody - NBP1-52840 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Septin-6 Antibody [NBP1-52840] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

Septin-6 Antibody (1D6) - H00023157-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D6
Western Blot: Septin-6 Antibody (1D6) [H00023157-M01] - SEPT6 monoclonal antibody (M01), clone 1D6. Analysis of SEPT6 expression in Jurkat.
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