Gene Symbol | DBR1 |
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Entrez Gene | 51163 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | debranching RNA lariats 1 |
Other Description | RNA lariat debranching enzyme|debranching enzyme homolog 1|lariat debranching enzyme |
Swissprots | Q96GH0 Q9NXQ6 Q9UK59 |
Accessions | EAW79083 Q9UK59 AF180919 AAD53327 AK000116 BAA90954 AK094147 BAG52827 AL702928 BC009472 AAH09472 BF987317 BM150284 CD677175 DQ895420 ABM86346 EU176332 ABW03783 NM_016216 NP_057300 |
Function | Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis. {ECO:0000269|PubMed:10982890, ECO:0000269|PubMed:16232320}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Human DBR1 full length protein - ab132751 from Abcam
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Human DBR1 protein fragment - ab171685 from Abcam
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DBR1 Recombinant Protein - H00051163-P01 from Novus Biologicals
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DBR1 Partial Recombinant Protein - H00051163-Q01 from Novus Biologicals
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Recombinant Human DBR1 Protein - NBP2-22991 from Novus Biologicals
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DBR1 protein (His tag) - 80R-3046 from Fitzgerald
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Human DBR1 Protein - abx066276 from Abbexa
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Human DBR1 Protein - abx066277 from Abbexa
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DBR1 (228-544, His-tag) - AR51164PU-N from Acris Antibodies
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DBR1 (228-544, His-tag) - AR51164PU-S from Acris Antibodies
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DBR1 - H00051163-P01-10 from Acris Antibodies
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DBR1 - H00051163-P01-25 from Acris Antibodies
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DBR1 - H00051163-Q01-10 from Acris Antibodies
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DBR1 - H00051163-Q01-25 from Acris Antibodies
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DBR1, 228-544aa, Human, His tag, E.coli - 01-P2340 from ARP American Research Products
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Debranching Enzyme Homolog 1 (DBR1), Human - 20-9363 from ARP American Research Products
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Debranching Enzyme Homolog 1 (DBR1), Human - 20-9364 from ARP American Research Products
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DBR1 fusion protein - Ag8830 from Proteintech Group
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Recombinant Human DBR1, His-tagged - DBR1-26123TH from Creative Biomart
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Recombinant Human DBR1, His-tagged - DBR1-11847H from Creative Biomart
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Recombinant Human DBR1, His-tagged - DBR1-2340H from Creative Biomart
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Recombinant Debranching Enzyme Homolog 1 (DBR1) - RPJ293Hu01 from Uscn Life Science Inc.
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Recombinant Debranching Enzyme Homolog 1 (DBR1) - RPJ293Hu02 from Uscn Life Science Inc.
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Recombinant Debranching Enzyme Homolog 1 (DBR1) - RPJ293Hu01 from Cloud-clone
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Recombinant Debranching Enzyme Homolog 1 (DBR1) - RPJ293Hu02 from Cloud-clone
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