Gene Symbol | GPI |
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Entrez Gene | 2821 |
Alt Symbol | AMF, GNPI, NLK, PGI, PHI, SA-36, SA36 |
Species | Human |
Gene Type | protein-coding |
Description | glucose-6-phosphate isomerase |
Other Description | autocrine motility factor|glucose phosphate isomerase|hexose monophosphate isomerase|hexosephosphate isomerase|neuroleukin|oxoisomerase|phosphoglucose isomerase|phosphohexomutase|phosphohexose isomerase|phosphosaccharomutase|sperm antigen 36|sperm antigen-36 |
Swissprots | Q9BSK5 Q9BRD3 Q9UHE6 B4DG39 P06744 |
Accessions | AAP72966 P06744 AB209575 BAD92812 AK025421 AK129884 AK130102 AK293446 BAG56947 AK294396 BAG57650 AK301103 BAG62702 BC004982 AAH04982 BC006342 BM664761 BX641158 CR745343 DC299841 DC342043 DQ892924 ABM83850 DQ896173 ABM87172 FY213211 K03515 AAA36368 X16539 XM_005258764 XP_005258821 XM_006723148 XP_006723211 XM_011526754 XP_011525056 XM_011526755 XP_011525057 NM_000175 NP_000166 NM_001184722 NP_001171651 NM_001289789 NP_001276718 NM_001289790 NP_001276719 |
Function | Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. {ECO:0000269|PubMed:11004567, ECO:0000269|PubMed:11437381}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11437381}. Secreted {ECO:0000269|PubMed:11437381}. |
Top Pathways | Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Amino sugar and nucleotide sugar metabolism, Carbon metabolism, Starch and sucrose metabolism |
GPI 293T Cell Transient Overexpression Lysate(Denatured) - H00002821-T01 from Acris Antibodies
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GPI 293T Cell Transient Overexpression Lysate(Denatured) - H00002821-T02 from Acris Antibodies
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GPI overexpression lysate - LY400066 from Acris Antibodies
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GPI overexpression lysate - LY433292 from Acris Antibodies
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GPI 293 Cell Lysate - 400156 from ABBIOTEC
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Glucose 6 phosphate isomerase Overexpression Lysate (Denatured) - H00002821-T01 from Novus Biologicals
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Glucose 6 phosphate isomerase Overexpression Lysate (Denatured) - H00002821-T02 from Novus Biologicals
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Glucose 6 phosphate isomerase Overexpression Lysate (Native) - NBL1-11230 from Novus Biologicals
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GPI (h2): 293T Lysate - sc-170846 from Santa Cruz Biotechnology
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GPI Over-expression Lysate Product - GWB-746D60 from Genway Biotech
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Human nemo-like kinase / NLK Insect Cell Lysate (WB positive control) - 11573-H20BL-300 from Sino Biological
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Human NLK Baculovirus-Insect Cells Transfected Lysate Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175192 from Biorbyt
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Glucose 6 phosphate isomerase Overexpression Lysate (Denatured) - H00002821-T03 from Novus Biologicals
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Panoply™ Human GPI Knockdown Stable Cell Line - CSC-DC006496 from Creative biogene
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Human GPI Knockout Cell Line-HEK293T - CSC-RT1265 from Creative biogene
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GPI KO Cell Lysate-HEK293T - CLKO-1118 from Creative biogene
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