KCNJ11

Gene Symbol	KCNJ11
Entrez Gene	3767
Alt Symbol	BIR, HHF2, IKATP, KIR6.2, PHHI, TNDM3
Species	Human
Gene Type	protein-coding
Description	potassium channel, inwardly rectifying subfamily J, member 11
Other Description	ATP-sensitive inward rectifier potassium channel 11|beta-cell inward rectifier subunit|inward rectifier K(+) channel Kir6.2|inwardly rectifying potassium channel KIR6.2|potassium channel inwardly rectifing subfamily J member 11|potassium channel, inwardly rectifying subfamily J member 11|potassium inwardly-rectifying channel, subfamily J, member 11
Swissprots	Q58EX3 Q2M1H7 Q8IW96 E9PNK0 B4DWI4 Q14654
Accessions	ACR44082 ACR44083 ACZ56124 AHB14393 AHB14394 AHB14395 BAA09131 EAW68438 Q14654 AI377272 AK301550 BAG63046 AK314943 BAG37449 BC040617 AAH40617 BC064497 AAH64497 BC112358 AAI12359 BE019467 XM_006718226 XP_006718289 XR_930867 NM_000525 NP_000516 NM_001166290 NP_001159762
Function	This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity). Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. {ECO:0000250, ECO:0000269|PubMed:17855752, ECO:0000269|PubMed:9831708}.
Subcellular Location	Membrane; Multi-pass membrane protein.
Top Pathways	Type II diabetes mellitus

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human KCNJ11 / Kir6.2 ELISA Kit (Cell-Based ELISA) - LS-F2110 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

Mouse/Human Phospho-KCNJ11 / Kir6.2 (Thr224) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1405 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

ATP Binding Cassette Transporter C8 (ABCC8), Human, ELISA Kit - SED628Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.128ng/mL Range 0.312-20ng/mL

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), Human, ELISA Kit - E01A1892 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Atp-Sensitive Inward Rectifier Potassium Channel 11, KCNJ11/Kir6.2, Human, ELISA Kit - YHB0427Hu from ARP American Research Products Category ELISA Kit

Kir6.2 Colorimetric Cell-Based ELISA Kit - CB5406 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Kir6.2 (Phospho-Thr224) Colorimetric Cell-Based ELISA Kit - CBP1432 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

ATP sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7224583 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11, ELISA Kit - MBS280155 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7200259 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7215689 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7237991 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7211640 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7232142 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7239826 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7223713 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7225276 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7209668 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7202534 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11 (KCNJ11), ELISA Kit - MBS7233525 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11, KCNJ11/Kir6.2, ELISA Kit - MBS9306896 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11, KCNJ11/Kir6.2, ELISA Kit - MBS9306452 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11, KCNJ11/Kir6.2, ELISA Kit - MBS9305945 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ATP-sensitive inward rectifier potassium channel 11, KCNJ11/Kir6.2, ELISA Kit - MBS9306980 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for ATP Binding Cassette Transporter C8 (ABCC8) - SED628Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.118ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

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