AGPAT3

Gene Symbol AGPAT3
Entrez Gene 56894
Alt Symbol LPAAT-GAMMA1, LPAAT3
Species Human
Gene Type protein-coding
Description 1-acylglycerol-3-phosphate O-acyltransferase 3
Other Description 1-AGP acyltransferase 3|1-AGPAT 3|1-acyl-sn-glycerol-3-phosphate acyltransferase gamma|lysophosphatidic acid acyltransferase gamma|lysophosphatidic acid acyltransferase-gamma1
Swissprots Q8N3Q7 Q6ZUC6 Q3ZCU2 Q9NRZ6 Q6UWP6 D3DSL2 Q9NRZ7
Accessions EAX09461 EAX09462 EAX09463 EAX09464 EAX09465 Q9NRZ7 AB040138 BAB18943 AF156774 AAF80336 AF156775 AAF80337 AK026135 AK074300 BAB85042 AK125804 BAC86299 AK300562 BAG62268 AL109795 AL355720 AL355721 AL832919 CAD38635 AY358704 AAQ89067 BC004219 BC004413 BC011971 AAH11971 BC013167 BC026047 BC040603 AAH40603 BC063552 AAH63552 BM083518 BM476336 CD672915 HQ447507 ADQ31993 XM_005261160 XP_005261217 XM_006724029 XP_006724092 XM_006724030 XP_006724093 XM_006724031 XP_006724094 XM_011529660 XP_011527962 XM_011529661 XP_011527963 XM_011529662 XP_011527964 XM_011529663 XP_011527965 XM_011529664 XP_011527966 XM_011529665 XP_011527967 XM_011529666 XP_011527968 NM_001037553 NP_001032642 NM_020132 NP_064517
Function Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA. {ECO:0000269|PubMed:21173190}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus envelope.
Tissue Specificity Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver. {ECO:0000269|PubMed:21173190}.
Top Pathways Glycerolipid metabolism, Glycerophospholipid metabolism

LPAAT-γ (E-16) - sc-83190 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
LPAAT-γ (E-16): sc-83190. Western blot analysis of LPAAT-γ expression in HEK293 (A), HeLa (B), OV-90 (C), NIH/3T3 (D) and SW480 (E) whole cell lysates.

Anti-AGPAT3 antibody - ab93181 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-AGPAT3 antibody (ab93181) at 1/100 dilution + A2058 cell line lysates at 35 µg

Anti-AGPAT3 antibody - ab107574 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AGPAT3 antibody (ab107574) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : Human fetal liver lysate

Anti-AGPAT3 antibody - ab135887 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-AGPAT3 antibody (ab135887) at 1/500 dilution + COLO205 cell lysate at 30 µg

Anti-AGPAT3 Antibody (Internal, APC) - LS-C243644 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGPAT3 Antibody (Internal, AP) - LS-C243643 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGPAT3 Antibody (Internal, Biotin) - LS-C243646 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGPAT3 Antibody (Internal, FITC) - LS-C243647 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGPAT3 Antibody (Internal, PE) - LS-C243650 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGPAT3 Antibody (aa145-194) - LS-C135884 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AGPAT3 antibody LS-C135884 Western blot of Fetal Liver lysate. Antibody concentration 1 ug/ml.

Anti-AGPAT3 Antibody (Internal, Azide-free, HRP) - LS-C247433 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGPAT3 Antibody (Internal) - LS-C326805 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGPAT3 Antibody (aa112-161) - LS-C200101 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from COLO205 cells using AGPAT3 antibody.

Anti-AGPAT4 Antibody (Internal) - LS-C326806 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AGPAT3 Antibody (aa121-170) IHC-plus™ - LS-B9677 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-AGPAT3 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9677 concentration 10 ug/ml.

Anti-AGPAT3 Antibody (aa241-269) - LS-C156154 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with AGPAT3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

AGPAT3 Antibody - NBP1-74276 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: AGPAT3 Antibody [NBP1-74276] - Human Fetal Liver Lysate 1ug/ml Gel Concentration 12%

AGPAT3 Antibody - H00056894-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: AGPAT3 Antibody [H00056894-A01] - Western Blot analysis of AGPAT3 expression in Hela NE ( Cat # L013V3 ).

Anti-AGPAT3 antibody produced in rabbit - SAB2107580 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-AGPAT3: <B>Cat. No. SAB2107580</B>: Western blot analysis of AGPAT3 in Fetal Liver with AGPAT3 (1-acylglycerol-3-phosphate O-acyltransferase 3) antibody against the middle region of AGPAT3 (50 μg) antibody at 1.0 μg/mL.

Anti-AGPAT3 antibody produced in rabbit - HPA057832 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AGPAT3: <B>Cat. No. HPA057832</B>: Immunohistochemical staining of Human kidney shows strong cytoplasmic positivity in tubular cells.

Anti-AGPAT3 antibody produced in rabbit - SAB4502435 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-AGPAT3: <B>Cat. No. SAB4502435</B>: Immunoblotting analysis of extracts from K562 cells, using Anti-AGPAT3 antibody. The lane on the left was treated with the Anti-AGPAT3 antibody. The lane on the right (negative control) was treated with both Anti-AGPAT3 antibody and the synthesized immunogen peptide.

Anti-AGPAT3 (203-215) antibody produced in rabbit - SAB1104761 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human AGPAT3 was separated on SDS-PAGE, blotted with Anti-AGPAT3 (203-215) (<B>Cat. No. SAB1104761</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500

ANTI-AGPAT3 (CENTER) antibody produced in rabbit - SAB1303003 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>AGPAT3 (Center): <B>Cat. No. SAB1303003</B>: AGPAT3 in Human brain tissue with AGPAT3 antibody (Center) at 5 μg/mL.

AGPAT3 antibody - middle region (ARP60800_P050) - ARP60800_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AGPAT3-Antibody-Center - AP8686c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of AGPAT3 Antibody (Center) (Cat. #AP8686c) in A2058 cell line lysates (35ug/lane). AGPAT3 (arrow) was detected using the purified Pab.
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