| Gene Symbol | KCNIP2 |
|---|---|
| Entrez Gene | 30819 |
| Alt Symbol | KCHIP2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | Kv channel interacting protein 2 |
| Other Description | A-type potassium channel modulatory protein 2|Kv channel-interacting protein 2|cardiac voltage-gated potassium channel modulatory subunit|potassium channel-interacting protein 2 |
| Swissprots | Q96T43 Q3YAC8 Q96T44 Q7Z6F1 A8MQ75 Q9HD11 Q9NY10 Q9H0N4 Q3YAC9 A6NJE5 Q9NZI1 Q3YAC6 Q96T42 Q9NS61 Q96K86 Q9NS60 Q96T41 Q9HD10 |
| Accessions | AAK21972 AAX58112 EAW49730 EAW49731 EAW49732 EAW49733 EAW49734 EAW49735 EAW49736 EAW49737 EAW49738 EAW49739 EAW49740 Q9NS61 AB044584 BAA96740 AB044585 BAA96741 AF199598 AAF33683 AF295076 AAG02120 AF295530 AAG02121 AF347114 AAK70356 AF367018 AAK53707 AF367019 AAK53708 AF367020 AAK53709 AF367021 AAK53710 AJ276317 CAB77054 AK027347 BAB55052 AK055089 BAG51465 AK094668 BAG52907 AK125382 AK130689 AK295324 BAG58301 AK301433 BAG62961 AK309368 AK314536 AK315042 BAG37523 AL136722 CAB66656 AM392816 CAL37694 AY026328 AAK07674 AY302141 AAP57633 BC034685 AAH34685 BG911444 DQ148480 AAZ77797 DQ148481 AAZ77798 DQ148482 AAZ77799 DQ148483 AAZ77800 DQ148484 AAZ77801 DQ862463 ABI51986 XM_005269729 XP_005269786 XM_005269730 XP_005269787 XM_006717812 XP_006717875 XM_011539731 XP_011538033 NM_014591 NP_055406 NM_173191 NP_775283 NM_173192 NP_775284 NM_173193 NP_775285 NM_173194 NP_775286 NM_173195 NP_775287 NM_173197 NP_775289 NM_173342 |
| Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart (By similarity). {ECO:0000250|UniProtKB:Q9JJ69, ECO:0000269|PubMed:10676964, ECO:0000269|PubMed:11287421, ECO:0000269|PubMed:11684073, ECO:0000269|PubMed:12297301, ECO:0000269|PubMed:12829703, ECO:0000269|PubMed:14623880}. |
| Subcellular Location | Isoform 6: Cell membrane {ECO:0000250|UniProtKB:Q9JM59}; Lipid-anchor {ECO:0000250|UniProtKB:Q9JM59}. |
| Tissue Specificity | Expressed in brain. Colocalizes with KCND2 in excitatory neurons including cortical and hippocampal CA1 pyramidal cells. Isoform 3 is expressed in heart and in umbilical vein endothelial cells. Not expressed in fetal heart. {ECO:0000269|PubMed:11263977, ECO:0000269|PubMed:11684073, ECO:0000269|PubMed:15356203}. |
Human KCNIP2 Gene cDNA Clone - orb143934 from Biorbyt
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Human-KCNIP2-cDNA-Clone - DC06771 from Abgent, a WuXi AppTec company
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KCNIP2 - MBS1269939 from MyBioSource
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Human KCNIP2 cDNA clone(NM_173191.2) - CDFG010643 from Creative Biomart
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Human KCNIP2 cDNA clone(NM_173193.2) - CDFG010645 from Creative Biomart
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Human KCNIP2 cDNA clone(NM_173192.2) - CDFG010646 from Creative Biomart
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Human KCNIP2 cDNA clone(NM_173195.2) - CDFG010647 from Creative Biomart
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Human KCNIP2 cDNA clone(NM_173194.2) - CDFG010649 from Creative Biomart
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Human KCNIP2 cDNA clone(NM_173197.2) - CDFG010651 from Creative Biomart
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Human KCNIP2 cDNA clone(NM_014591.4) - CDFH009636 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_014591.4) - CDCL167714 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_014591.4) - CDCR297862 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_014591.4) - CDCR297863 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173191.2) - CDCR321461 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173192.2) - CDCR321462 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173192.2) - CDCR321463 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173192.2) - CDCR321464 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173193.2) - CDCR321465 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173193.2) - CDCR321466 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173194.2) - CDCR321467 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173194.2) - CDCR321468 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173195.2) - CDCR321469 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173195.2) - CDCR321470 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173191.2) - CDCR321760 from Creative Biomart
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Human KCNIP2 ORF Clone(NM_173197.2) - CDCR321761 from Creative Biomart
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