KCNIP2

Gene Symbol KCNIP2
Entrez Gene 30819
Alt Symbol KCHIP2
Species Human
Gene Type protein-coding
Description Kv channel interacting protein 2
Other Description A-type potassium channel modulatory protein 2|Kv channel-interacting protein 2|cardiac voltage-gated potassium channel modulatory subunit|potassium channel-interacting protein 2
Swissprots Q96T43 Q3YAC8 Q96T44 Q7Z6F1 A8MQ75 Q9HD11 Q9NY10 Q9H0N4 Q3YAC9 A6NJE5 Q9NZI1 Q3YAC6 Q96T42 Q9NS61 Q96K86 Q9NS60 Q96T41 Q9HD10
Accessions AAK21972 AAX58112 EAW49730 EAW49731 EAW49732 EAW49733 EAW49734 EAW49735 EAW49736 EAW49737 EAW49738 EAW49739 EAW49740 Q9NS61 AB044584 BAA96740 AB044585 BAA96741 AF199598 AAF33683 AF295076 AAG02120 AF295530 AAG02121 AF347114 AAK70356 AF367018 AAK53707 AF367019 AAK53708 AF367020 AAK53709 AF367021 AAK53710 AJ276317 CAB77054 AK027347 BAB55052 AK055089 BAG51465 AK094668 BAG52907 AK125382 AK130689 AK295324 BAG58301 AK301433 BAG62961 AK309368 AK314536 AK315042 BAG37523 AL136722 CAB66656 AM392816 CAL37694 AY026328 AAK07674 AY302141 AAP57633 BC034685 AAH34685 BG911444 DQ148480 AAZ77797 DQ148481 AAZ77798 DQ148482 AAZ77799 DQ148483 AAZ77800 DQ148484 AAZ77801 DQ862463 ABI51986 XM_005269729 XP_005269786 XM_005269730 XP_005269787 XM_006717812 XP_006717875 XM_011539731 XP_011538033 NM_014591 NP_055406 NM_173191 NP_775283 NM_173192 NP_775284 NM_173193 NP_775285 NM_173194 NP_775286 NM_173195 NP_775287 NM_173197 NP_775289 NM_173342
Function Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart (By similarity). {ECO:0000250|UniProtKB:Q9JJ69, ECO:0000269|PubMed:10676964, ECO:0000269|PubMed:11287421, ECO:0000269|PubMed:11684073, ECO:0000269|PubMed:12297301, ECO:0000269|PubMed:12829703, ECO:0000269|PubMed:14623880}.
Subcellular Location Isoform 6: Cell membrane {ECO:0000250|UniProtKB:Q9JM59}; Lipid-anchor {ECO:0000250|UniProtKB:Q9JM59}.
Tissue Specificity Expressed in brain. Colocalizes with KCND2 in excitatory neurons including cortical and hippocampal CA1 pyramidal cells. Isoform 3 is expressed in heart and in umbilical vein endothelial cells. Not expressed in fetal heart. {ECO:0000269|PubMed:11263977, ECO:0000269|PubMed:11684073, ECO:0000269|PubMed:15356203}.

KChIP2 CRISPR/Cas9 KO Plasmid (h) - sc-403327 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KChIP2 HDR Plasmid (h) - sc-403327-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KChIP2 Double Nickase Plasmid (h) - sc-403327-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KChIP2 Double Nickase Plasmid (h2) - sc-403327-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KChIP2 CRISPR Activation Plasmid (h) - sc-403327-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KChIP2 CRISPR Activation Plasmid (h2) - sc-403327-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

KChIP2 Lentiviral Activation Particles (h) - sc-403327-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KChIP2 Lentiviral Activation Particles (h2) - sc-403327-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

KChIP2 siRNA (h) - sc-42402 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KChIP2 shRNA Plasmid (h) - sc-42402-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KChIP2 shRNA (h) Lentiviral Particles - sc-42402-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KChIP2 RNAi - H00030819-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: KChIP2 RNAi [H00030819-R01V] - Analysis of KCNIP2 over-expressed 293 cell line, cotransfected with KCNIP2 Validated Chimera RNAi or non-transfected control. Blot probed with H00030819-M01. GAPDH (36.1 kDa) used as loading control.

KChIP2 RNAi - H00030819-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KChIP2 RNAi - H00030819-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KChIP2 RNAi - H00030819-R07 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KChIP2 RNAi - H00030819-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KChIP2 RNAi - H00030819-R08 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KChIP2 RNAi - H00030819-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KChIP2 RNAi - H00030819-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

KChIP2 RNAi - H00030819-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU099261 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU061301 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10950 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10950 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KCNIP2 siRNA (Human) - CRH9346 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human
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