LRRC8C

Gene Symbol LRRC8C
Entrez Gene 84230
Alt Symbol AD158, FAD158
Species Human
Gene Type protein-coding
Description leucine rich repeat containing 8 family, member C
Other Description factor for adipocyte differentiation 158|hypothetical protein AD158|leucine rich repeat containing 8C|leucine-rich repeat-containing protein 8C|volume-regulated anion channel subunit LRRC8C
Swissprots Q8TDW0 B3KXS9 Q29RV6 Q9H075
Accessions CBX47551 EAW73134 Q8TDW0 AB081509 BAB86303 AI014679 AK094804 AK127881 BAG54591 AL136919 CAB66853 AL699030 BC036122 AAH36122 BC103929 BC113973 AAI13974 HG492250 XM_006710960 XP_006711023 XM_011542282 XP_011540584 XM_011542283 XP_011540585 XM_011542284 XP_011540586 XM_011542285 XP_011540587 NM_032270 NP_115646
Function Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8C constitutes a pore-forming subunit or whether it is closely associated with the pore. May play a role in adipogenesis (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Expressed at highest levels in skeletal muscle, and at moderate levels in heart, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:15564382}.

LRRC8C (H-45) - sc-135294 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

LRRC8C (T-13) - sc-161807 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LRRC8C (T-13): sc-161807. Western blot analysis of LRRC8C expression in rat heart tissue extract.

Anti-LRRC8C antibody - ab122046 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of Human cell line U-2 OS shows positivity in golgi apparatus. Recommended concentration of ab122046 1-4 µg/ml. Cells treated with PFA/Triton X-100.

LRRC8C Antibody - NBP1-90871 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: LRRC8C Antibody [NBP1-90871] - Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.

LRRC8C antibody - 70R-18313 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

LRRC8C antibody - 21601-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human heart using 21601-1-AP(LRRC8C antibody) at dilution of 1:50 (under 40x lens)

LRRC8C antibody - 21601-1-AP from Proteintech Group

Prices $279.00
Sizes con: 70 μg/150μl
Host Rabbit
Clonality Polyclonal
Immunohistochemical of paraffin-embedded human heart using 21601-1-AP(LRRC8C antibody) at dilution of 1:50 (under 10x lens)

leucine rich repeat containing 8 family, member C , Polyclonal Antibody - MBS711316 from MyBioSource

Prices $230.00, $500.00
Sizes 50 µl, 150 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8C (aa 662-792) polyclonal antibody - DPABH-20365 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

LRRC8C, Polyclonal Antibody - MBS838943 from MyBioSource

Prices $490.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-LRRC8C antibody produced in rabbit - HPA029347 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LRRC8C: <B>Cat. No. HPA029347</B>: Immunohistochemical staining of human colon shows strong nuclear membrane and cytoplasmic positivity in glandular cells.

LRRC8C Antibody - SH-A13368 from Novatein Biosciences

Prices $315.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

LRRC8C antibody (FITC) - orb189369 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

anti-LRRC8C antibody - A004861 from Biobool

Host Rabbit
Clonality Polyclonal

LRRC8C, Polyclonal Antibody - MBS7601094 from MyBioSource

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

LRRC8C antibody - orb185055 from Biorbyt

Host Rabbit
Clonality Polyclonal
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